Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14326991 | 0.85 | TAAR1 (0.61) | TAAR1CHRM2CHRM1CHRM3ATM | |
| SCHEMBL241880 | 0.84 | CYP4F2 (0.53) | TAAR1TBXA2RALOX15LMNAMEN1 | |
| SCHEMBL3052902 | 0.83 | TAAR1 (0.59) | TAAR1CHRM2CHRM1CHRM3ATM | |
| SCHEMBL2911337 | 0.79 | TAAR1 (0.63) | TAAR1CHRM2CHRM1CHRM3ATM | |
| SCHEMBL8464457 | 0.79 | CYP4F2 (0.54) | TBXA2RMAPK1HPGDNPSR1CYP4F2 | |
| SCHEMBL2906778 | 0.79 | TAAR1 (0.63) | TAAR1CHRM2CHRM1CHRM3ATM | |
| SCHEMBL80185 | 0.79 | CYP4A11 (0.58) | TBXA2RTP53CYP4F2CYP4A11NOS1 | |
| SCHEMBL1244841 | 0.78 | CYP4F2 (0.49) | TBXA2RALOX15TSHRMEN1KMT2A | |
| Dimethylamine SCHEMBL9872133 | 0.78 | TAAR1 (0.53) | TAAR1MEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL5186512 | 0.78 | CYP4A11 (0.47) | TBXA2RCYP4F2CYP4A11SIGMAR1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168944-A1 | AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2010-03-31 | — | — | EP | disclosed |