SCHEMBL1244841

SCHEMBL1244841

OCCCc1cccc(CO)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.49
CYP4A11 Q02928 2/20 0.49
ENPP2 Q13822 1/20 0.47
TBXA2R P21731 1/20 0.46
DAO P14920 1/20 0.46
NOS1 P29475 2/20 0.44
TSHR P16473 1/20 0.44
PRSS1 P07477 1/20 0.44
PRSS2 P07478 1/20 0.44
PRSS3 P35030 1/20 0.44
LTA4H P09960 1/20 0.43
EPHX2 P34913 1/20 0.43
PRKCI P41743 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
CYP11B1 P15538 1/20 0.41
CYP11B2 P19099 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CYP2D6 P10635 1/20 0.39
NOS3 P29474 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL241880 0.93 CYP4F2 (0.53) CYP4F2CYP4A11TBXA2RNOS1LTA4H
SCHEMBL10922837 0.91 CYP4F2 (0.51) CYP4F2CYP4A11ENPP2TBXA2RDAO
SCHEMBL11491469 0.86 ENPP2 (0.50) CYP4F2CYP4A11ENPP2DAONOS1
SCHEMBL238401 0.86 CYP4F2 (0.58) CYP4F2CYP4A11TBXA2RNOS1TDP1
SCHEMBL2138580 0.86 TDP1 (0.56) CYP4F2CYP4A11ENPP2DAONOS1
SCHEMBL2176833 0.84 CYP4F2 (0.56) CYP4F2CYP4A11TBXA2RNOS1IGF1R
SCHEMBL80185 0.83 CYP4A11 (0.58) CYP4F2CYP4A11TBXA2RNOS1LTA4H
SCHEMBL613331 0.83 TAAR1 (0.48) CYP4F2CYP4A11TBXA2RNOS1LTA4H
SCHEMBL13959482 0.83 TAAR1 (0.48) ENPP2DAONOS1TSHRPRSS1
SCHEMBL8464457 0.83 CYP4F2 (0.54) CYP4F2CYP4A11TBXA2RLPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104262921-B A kind of bamboo fiber strengthens without styrene unsaturated polyester composite and preparation thereof Fujian Agricultural and Forestry University (CN) 2016-05-11 CN claimed
CN-104262921-A Bamboo fiber reinforced styrene-free unsaturated polyester composite material and preparation method thereof UNIV FUJIAN AGRIC & FORESTRY 2015-01-07 CN claimed
US-9382188-B2 Aromatic ring compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-07-05 US disclosed
CN-104262921-B A kind of bamboo fiber strengthens without styrene unsaturated polyester composite and preparation thereof Fujian Agricultural and Forestry University (CN) 2016-05-11 CN disclosed
CN-104262921-B A kind of bamboo fiber strengthens without styrene unsaturated polyester composite and preparation thereof Fujian Agricultural and Forestry University (CN) 2016-05-11 CN disclosed
CN-104262921-A Bamboo fiber reinforced styrene-free unsaturated polyester composite material and preparation method thereof UNIV FUJIAN AGRIC & FORESTRY 2015-01-07 CN disclosed
EP-2816023-A1 AROMATIC RING COMPOUND Takeda Pharmaceutical Company Limited (JP) 2014-12-24 EP disclosed
US-8476265-B2 Compounds-801 ASTRAZENECA AB (SE) 2013-07-02 US disclosed
US-8476265-B2 Compounds-801 ASTRAZENECA AB (SE) 2013-07-02 US disclosed
US-8476265-B2 Compounds-801 ASTRAZENECA AB (SE) 2013-07-02 US disclosed
US-8455483-B2 Compounds—801 ASTRAZENECA AB (SE) 2013-06-04 US disclosed
US-20130018037-A1 Compounds - 801 ASTRAZENECA UK LIMITED (GB) 2013-01-17 US disclosed
US-20130018037-A1 Compounds - 801 ASTRAZENECA UK LIMITED (GB) 2013-01-17 US disclosed
US-20130018037-A1 Compounds - 801 ASTRAZENECA UK LIMITED (GB) 2013-01-17 US disclosed
EP-2459572-A2 SPIROCYCLIC AMIDE DERIVATIVES AstraZeneca AB (SE) 2012-06-06 EP disclosed
US-20110053909-A1 Compounds - 801 PULMAGEN THERAPEUTICS (SYNERGY) LIMITED (GB) 2011-03-03 US disclosed
US-20110053909-A1 Compounds - 801 PULMAGEN THERAPEUTICS (SYNERGY) LIMITED (GB) 2011-03-03 US disclosed
US-20110053909-A1 Compounds - 801 PULMAGEN THERAPEUTICS (SYNERGY) LIMITED (GB) 2011-03-03 US disclosed
WO-2011012896-A2 COMPOUNDS - 801 ASTRAZENECA AB (SE) 2011-02-03 WO disclosed
WO-2011012896-A2 COMPOUNDS - 801 ASTRAZENECA AB (SE) 2011-02-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130018037-A1 Compounds - 801 ADRA2C, ADRB2, ADRB1 CYP4F2 874/4885CYP4A11 252/4885ENPP2 3495/4885
US-20110053909-A1 Compounds - 801 ADRA2C, ADRB2, ADRB1 CYP4F2 874/4885CYP4A11 252/4885ENPP2 3495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.