SCHEMBL80185

SCHEMBL80185

CCc1cccc(CCCO)c1

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP4A11 Q02928 4/20 0.58
CYP4F2 P78329 3/20 0.58
LPL P06858 2/20 0.44
LIPG Q9Y5X9 2/20 0.44
TBXA2R P21731 1/20 0.44
NOS1 P29475 1/20 0.42
TP53 P04637 1/20 0.41
LTA4H P09960 1/20 0.41
EPHX2 P34913 1/20 0.41
BCL2 P10415 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9111608 0.94 CYP4F2 (0.58) CYP4A11CYP4F2LPLLIPGTBXA2R
SCHEMBL13703310 0.92 CYP4F2 (0.57) CYP4A11CYP4F2LPLLIPG
SCHEMBL241880 0.89 CYP4F2 (0.53) CYP4A11CYP4F2LPLLIPGTBXA2R
SCHEMBL8464457 0.88 CYP4F2 (0.54) CYP4A11CYP4F2LPLLIPGTBXA2R
SCHEMBL1247008 0.87 CYP4F2 (0.55) CYP4A11CYP4F2TP53BCL2
SCHEMBL28150919 0.84 LPL (0.62) CYP4A11CYP4F2LPLLIPGTP53
SCHEMBL1244841 0.83 CYP4F2 (0.49) CYP4A11CYP4F2LPLLIPGTBXA2R
SCHEMBL12510875 0.83 LPL (0.52) LPLLIPGTP53
SCHEMBL238401 0.82 CYP4F2 (0.58) CYP4A11CYP4F2LPLLIPGTBXA2R
SCHEMBL9490025 0.82 TP53 (0.52) NOS1TP53BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9376385-B2 Solid-phase supports and uses thereof INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2016-06-28 US disclosed
EP-2168944-B1 AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF MITSUBISHI TANABE PHARMA CORP (JP) 2016-05-11 EP disclosed
EP-2168944-B1 AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF MITSUBISHI TANABE PHARMA CORP (JP) 2016-05-11 EP disclosed
US-20150240006-A1 Solid-Phase Supports and Uses Thereof INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION 2015-08-27 US disclosed
CN-101730677-B Amine compound and pharmaceutical use thereof MITSUBISHI TANABE PHARMA CORP 2014-07-16 CN disclosed
CN-103907230-A Method for manufacturing fuel cell, fuel cell, and electronic device SONY CORP 2014-07-02 CN disclosed
US-8129361-B2 Amine compound and pharmaceutical use thereof MITSUBISHI TANABE PHARMA CORPORATION (JP) 2012-03-06 US disclosed
US-8129361-B2 Amine compound and pharmaceutical use thereof MITSUBISHI TANABE PHARMA CORPORATION (JP) 2012-03-06 US disclosed
US-8129361-B2 Amine compound and pharmaceutical use thereof MITSUBISHI TANABE PHARMA CORPORATION (JP) 2012-03-06 US disclosed
US-20100179216-A1 AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF MITSUBISHI TANABE PHARMA CORPORATION (JP) 2010-07-15 US disclosed
US-20100179216-A1 AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF MITSUBISHI TANABE PHARMA CORPORATION (JP) 2010-07-15 US disclosed
CN-101730677-A Amine compound and pharmaceutical use thereof MITSUBISHI TANABE PHARMA CORP 2010-06-09 CN disclosed
EP-2168944-A1 AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF Mitsubishi Tanabe Pharma Corporation (JP) 2010-03-31 EP disclosed
EP-2168944-A1 AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF Mitsubishi Tanabe Pharma Corporation (JP) 2010-03-31 EP disclosed
EP-0411150-B1 INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME OTSUKA PHARMA CO LTD (JP) 1996-11-27 EP disclosed
US-5459142-A Autoimmune disease, atherosclerosis, antiischemic agents and nephritis OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-10-17 US disclosed
EP-0511879-B1 Pyrazine derivatives OTSUKA PHARMA CO LTD (JP) 1995-03-22 EP disclosed
US-5238938-A Nephrosis OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-08-24 US disclosed
EP-0511879-A1 Pyrazine derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-11-04 EP disclosed
EP-0411150-A1 INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-02-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150240006-A1 Solid-Phase Supports and Uses Thereof ACR, ALK, ALKBH3 CYP4A11 3752/4885CYP4F2 2361/4885LPL 2149/4885
US-20100179216-A1 AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF HLA-B, HLA-A, HLA-C CYP4A11 41/4885CYP4F2 238/4885LPL 2361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.