Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.52 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.52 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.52 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | CDC25B | P30305 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | PTPRC | P08575 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | S100A4 | P26447 | 3/20 | 0.46 |
| ▸ | BLM | P54132 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | APAF1 | O14727 | 2/20 | 0.46 |
| ▸ | TDP2 | O95551 | 2/20 | 0.46 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL917548 | 0.79 | IDO1 (0.56) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| SCHEMBL29633271 | 0.79 | IDO1 (0.56) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| SCHEMBL13894576 | 0.76 | MAPT (0.52) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| SCHEMBL13894577 | 0.76 | CDC25B (0.63) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| SCHEMBL7997569 | 0.76 | SLC2A1 (0.57) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| SCHEMBL5091710 | 0.74 | CDC25B (0.48) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| SCHEMBL10345725 | 0.72 | KMT2A (0.42) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| SCHEMBL10343653 | 0.71 | TTR (0.43) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| SCHEMBL16138415 | 0.71 | CDC25B (0.67) | IDO1DNMT1DNMT3LDNMT3AMEN1 | |
| SCHEMBL2529860 | 0.70 | PTPRC (0.59) | IDO1DNMT1DNMT3LDNMT3AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010023686-A2 | CRYSTALLINE FORM OF 2-CHLORO-3-[4-(4-CHLOROPHENYL) CYCLOHEXYL] [1,4]NAPHTHOQUINONE, PROCESS FOR THE SAME AND USE FOR PRODUCING 2-[4-(4-CHLOROPHENYL)CYCLOHEXYL]-3- HYDROXY- 1,4- NAPHTHOQUINONE | MATRIX LABORATORIES LIMITED (IN) | 2010-03-04 | — | — | WO | disclosed |