Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | CDC25A | P30304 | 5/20 | 0.63 |
| ▸ | IDO1 | P14902 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | BLM | P54132 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.63 |
| ▸ | TP53 | P04637 | 4/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.63 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.63 |
| ▸ | MAOA | P21397 | 2/20 | 0.63 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13840594 | 0.83 | CDC25B (0.52) | CDC25BMAPTALDH1A1CDC25AIDO1 | |
| Menadione SCHEMBL19356853 | 0.77 | MAPT (1.00) | CDC25BMAPTALDH1A1CDC25AIDO1 | |
| Menadione SCHEMBL25970 | 0.77 | MAPT (1.00) | CDC25BMAPTALDH1A1CDC25AIDO1 | |
| Menadione SCHEMBL1364028 | 0.77 | MAPT (1.00) | CDC25BMAPTALDH1A1CDC25AIDO1 | |
| SCHEMBL7146635 | 0.77 | CDC25B (0.68) | CDC25BMAPTALDH1A1CDC25AIDO1 | |
| SCHEMBL7140356 | 0.77 | CDC25B (0.68) | CDC25BMAPTALDH1A1CDC25AIDO1 | |
| Menadione SCHEMBL29351164 | 0.77 | MAPT (1.00) | CDC25BMAPTALDH1A1CDC25AIDO1 | |
| Menadione SCHEMBL9807661 | 0.76 | MAPT (0.95) | CDC25BMAPTALDH1A1CDC25AIDO1 | |
| SCHEMBL13464147 | 0.76 | IDO1 (0.52) | CDC25BMAPTALDH1A1CDC25AIDO1 | |
| Menadione SCHEMBL9812440 | 0.76 | MAPT (0.95) | CDC25BMAPTALDH1A1CDC25AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009042544-A1 | QUINONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2009-04-02 | — | — | WO | disclosed |