Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.57 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.50 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.50 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.50 |
| ▸ | S100A4 | P26447 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | CDC25B | P30305 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | PTPRC | P08575 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL917548 | 0.77 | IDO1 (0.56) | IDO1DNMT1DNMT3LDNMT3AS100A4 | |
| SCHEMBL29633271 | 0.77 | IDO1 (0.56) | IDO1DNMT1DNMT3LDNMT3AS100A4 | |
| Hydrogen Sulfide SCHEMBL28329325 | 0.76 | IDO1 (0.54) | IDO1DNMT1DNMT3LDNMT3AS100A4 | |
| SCHEMBL13464147 | 0.76 | IDO1 (0.52) | IDO1DNMT1DNMT3LDNMT3AS100A4 | |
| SCHEMBL3273421 | 0.74 | SLC2A1 (0.96) | SLC2A1IDO1DNMT1DNMT3LDNMT3A | |
| SCHEMBL5091710 | 0.73 | CDC25B (0.48) | IDO1DNMT1DNMT3LDNMT3AS100A4 | |
| Hydrochloric Acid SCHEMBL29365758 | 0.72 | SLC2A1 (1.00) | SLC2A1IDO1DNMT1DNMT3LDNMT3A | |
| Hydrochloric Acid SCHEMBL3343803 | 0.72 | SLC2A1 (1.00) | SLC2A1IDO1DNMT1DNMT3LDNMT3A | |
| SCHEMBL2799752 | 0.69 | SLC2A1 (0.56) | SLC2A1IDO1DNMT1DNMT3LDNMT3A | |
| SCHEMBL2529860 | 0.68 | PTPRC (0.59) | IDO1DNMT1DNMT3LDNMT3AS100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010005534-A2 | PROTEASOME INHIBITORS FOR SELECTIVELY INDUCING APOPTOSIS IN CANCER CELLS | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2010-01-14 | — | — | WO | disclosed |