Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.54 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.41 |
| ▸ | DRD2 | P14416 | 7/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | TFPI | P10646 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13446002 | 0.83 | KEAP1 (0.46) | OPRK1 | |
| SCHEMBL13464210 | 0.82 | FOLH1 (0.38) | OPRK1OPRM1 | |
| SCHEMBL18054016 | 0.80 | KEAP1 (0.43) | OPRK1DRD2 | |
| SCHEMBL13446007 | 0.71 | KEAP1 (0.45) | OPRK1DRD2 | |
| SCHEMBL13446016 | 0.70 | KEAP1 (0.45) | OPRK1DRD2 | |
| SCHEMBL18762749 | 0.68 | CCKAR (0.43) | OPRK1 | |
| SCHEMBL18762750 | 0.67 | FOLH1 (0.50) | — | |
| SCHEMBL13892137 | 0.66 | OPRK1 (0.51) | OPRK1DRD2 | |
| SCHEMBL13445984 | 0.66 | KEAP1 (0.51) | — | |
| SCHEMBL9920121 | 0.66 | OPRK1 (0.50) | OPRK1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293206-B2 | Achievement of a high therapeutic index through molecular imaging guided targeted drug treatment | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2012-10-23 | — | — | US | disclosed |
| US-20100074910-A1 | Achievement of a high therapeutic index through molecular imaging guided targeted drug treatment | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100074910-A1 | Achievement of a high therapeutic index through molecular imaging guided targeted drug treatment | MKI67, CD47, CD68 | OPRK1 2532/4885OPRL1 1134/4885DRD2 3701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.