Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29388389 | 1.00 | ALDH1A1 (0.44) | ALDH1A1HPGDLMNAKMT2AKDM4E | |
| SCHEMBL595428 | 0.90 | ALDH1A1 (0.48) | ALDH1A1HPGDLMNAKMT2AKDM4E | |
| SCHEMBL13192768 | 0.84 | ALDH1A1 (0.43) | ALDH1A1HPGDLMNAKMT2AKDM4E | |
| SCHEMBL14889179 | 0.80 | ALDH1A1 (0.40) | ALDH1A1HPGDLMNAKMT2AKDM4E | |
| SCHEMBL20668832 | 0.80 | LMNA (0.40) | ALDH1A1HPGDLMNAKMT2AKDM4E | |
| SCHEMBL21268666 | 0.80 | ALDH1A1 (0.40) | ALDH1A1HPGDLMNAKMT2AKDM4E | |
| SCHEMBL1389181 | 0.79 | SMN1; SMN2 (0.45) | ALDH1A1HPGDLMNAKMT2AKDM4E | |
| SCHEMBL8681369 | 0.79 | ALDH1A1 (0.46) | ALDH1A1HPGDLMNAKMT2AKDM4E | |
| SCHEMBL21268691 | 0.79 | LMNA (0.37) | ALDH1A1HPGDLMNAKMT2AKDM4E | |
| SCHEMBL21268640 | 0.78 | LMNA (0.39) | ALDH1A1HPGDLMNAKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |
| CN-111978327-B | Preparation method of ticagrelor | 南京一心和医药科技有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-111978327-A | Preparation method of ticagrelor | 南京一心和医药科技有限公司 | 2020-11-24 | — | — | CN | disclosed |
| CN-107580596-A | For treating and preventing the new sulphur imido acyl group purinone compound and derivative of virus infection | 豪夫迈·罗氏有限公司 | 2018-01-12 | — | — | CN | disclosed |
| US-9604991-B2 | Preparation method of ticagrelor and intermediates thereof | SUZHOU MIRACPHARMA TECHNOLOGY CO., LTD. (CN) | 2017-03-28 | — | — | US | disclosed |
| WO-2013092900-A1 | SYNTHESIS OF TRIAZOLOPYRIMIDINE COMPOUNDS | LEK PHARMACEUTICALS D.D. (SI) | 2013-06-27 | — | — | WO | disclosed |
| WO-2010030224-A1 | A PROCESS FOR PREPARING [1S- [1-ALPHA, 2-ALPHA, 3-BETA (1S*, 2R*) 5-BETA] ] -3- [7- [2- (3, 4-DIF LUOROPHENYL) -CYCLOPROPYLAMINO] - 5- (PROPYLTHIO) -3H-1, 2, 3-TRIAZOLO [4, 5-D] PYRIMIDIN-3-YL] -5- (2- HYDROXYETHOXY) CYCLOPENTANE-1, 2-DIOL AND TO ITS INTERMEDIATES | ASTRAZENECA AB (SE) | 2010-03-18 | — | — | WO | disclosed |