Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.51 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | FLT3 | P36888 | 2/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13465512 | 0.92 | MAPT (0.54) | MAPTSLC6A7KDM4EALDH1A1NPSR1 | |
| SCHEMBL2310298 | 0.81 | MAPT (0.54) | MAPTSLC6A7KDM4EALDH1A1NPSR1 | |
| SCHEMBL2314529 | 0.81 | MAPT (0.54) | MAPTSLC6A7KDM4EALDH1A1NPSR1 | |
| SCHEMBL12206779 | 0.81 | MAPT (0.54) | MAPTSLC6A7KDM4EALDH1A1NPSR1 | |
| SCHEMBL20305868 | 0.74 | JMJD6 (0.62) | MAPTKDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL13465581 | 0.73 | MAPT (0.55) | MAPTSLC6A7KDM4EALDH1A1LMNA | |
| SCHEMBL12206749 | 0.73 | MAPT (0.77) | MAPTSLC6A7KDM4EALDH1A1LMNA | |
| SCHEMBL2307404 | 0.72 | MAPK1 (0.62) | MAPTKDM4EALDH1A1LMNANPSR1 | |
| SCHEMBL23259361 | 0.71 | SLC6A7 (0.60) | MAPTSLC6A7KDM4EALDH1A1LMNA | |
| SCHEMBL2312575 | 0.70 | ME2 (0.64) | MAPTSLC6A7KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010028776-A1 | PIPERAZINE DERIVATIVES FOR BINDING AND IMAGING AMYLOID PLAQUES AND THEIR USE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-03-18 | — | — | WO | disclosed |