Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | GJB2 | P29033 | 4/20 | 0.40 |
| ▸ | TLR4 | O00206 | 2/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.38 |
| ▸ | FGF1 | P05230 | 3/20 | 0.38 |
| ▸ | FGF2 | P09038 | 3/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12837370 | 1.00 | TNF (0.41) | TNFGJB2TLR4DGKAHPSE | |
| SCHEMBL12837368 | 0.94 | TLR4 (0.42) | TNFTLR4DGKAHPSEFGF1 | |
| SCHEMBL12837128 | 0.81 | GJB2 (0.45) | TNFGJB2HPSEFGF1FGF2 | |
| SCHEMBL13444803 | 0.81 | GJB2 (0.43) | TNFGJB2TLR4HPSEFGF1 | |
| SCHEMBL18311512 | 0.80 | GJB2 (0.49) | TNFGJB2TLR4HPSEFGF1 | |
| SCHEMBL19479699 | 0.80 | TNF (0.42) | TNFTLR4HPSEFGF1FGF2 | |
| SCHEMBL15999882 | 0.80 | TLR4 (0.65) | TNFGJB2TLR4HPSEFGF1 | |
| SCHEMBL15756255 | 0.80 | TLR4 (0.65) | TNFGJB2TLR4HPSEFGF1 | |
| SCHEMBL15756211 | 0.80 | TLR4 (0.65) | TNFGJB2TLR4HPSEFGF1 | |
| SCHEMBL15756236 | 0.80 | TLR4 (0.65) | TNFGJB2TLR4HPSEFGF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120263649-A1 | DETECTION OF MYCOBACTERIA | ISIS INNOVATION LIMITED (GB) | 2012-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120263649-A1 | DETECTION OF MYCOBACTERIA | LY96, MICA, CD74 | TNF 3603/4885GJB2 3072/4885TLR4 2439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.