Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | USP1 | O94782 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16131135 | 0.86 | PLA2G1B (0.33) | PLA2G1BATG4BPDK2USP1ACACB | |
| SCHEMBL13466373 | 0.85 | PLA2G1B (0.47) | PLA2G1BATG4BDRD3ACACBTDP1 | |
| SCHEMBL16131993 | 0.84 | TDP1 (0.48) | PDK2DRD3USP1TDP1NPC1 | |
| SCHEMBL13279403 | 0.83 | PDK2 (0.41) | PDK2DRD3CSF1RKDM5ASCN9A | |
| SCHEMBL13466364 | 0.79 | PLA2G1B (0.45) | PLA2G1BATG4BACACBTDP1NPC1 | |
| SCHEMBL13466369 | 0.75 | PRMT5 (0.35) | USP1ACACBTDP1LMNAHRH3 | |
| SCHEMBL10329767 | 0.73 | SMN1; SMN2 (0.58) | PLA2G1BATG4BDRD3TDP1NPC1 | |
| SCHEMBL12186155 | 0.73 | KMT2A (0.54) | PLA2G1BATG4BTDP1NPC1MAPT | |
| SCHEMBL26772953 | 0.72 | HRH3 (0.53) | PLA2G1BATG4BTDP1NPC1MAPT | |
| SCHEMBL24370438 | 0.71 | TDP1 (0.48) | PLA2G1BATG4BDRD3TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012142329-A1 | COMPOSITIONS AND THERAPEUTIC USES OF IKK-RELATED KINASE EPSILON AND TANKBINDING KINASE 1 INHIBITORS | MYREXIS, INC. (US) | 2012-10-18 | — | — | WO | disclosed |