Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | IL6 | P05231 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16131130 | 0.80 | CHRM2 (0.38) | L3MBTL1TLR7MEN1KMT2AMLYCD | |
| SCHEMBL14665823 | 0.80 | L3MBTL1 (0.42) | L3MBTL1HTTTLR7MEN1KMT2A | |
| SCHEMBL20332789 | 0.79 | L3MBTL1 (0.39) | L3MBTL1HTTMEN1KMT2A | |
| SCHEMBL14659877 | 0.78 | TLR7 (0.42) | L3MBTL1HTTTLR7KDM4ERECQL | |
| SCHEMBL17409833 | 0.77 | TLR7 (0.46) | L3MBTL1HTTTLR7MEN1KMT2A | |
| SCHEMBL17403532 | 0.76 | KMT2A (0.39) | L3MBTL1HTTTLR7MEN1KMT2A | |
| SCHEMBL10223307 | 0.76 | L3MBTL1 (0.97) | L3MBTL1HTTMEN1KMT2ANPC1 | |
| SCHEMBL13466404 | 0.75 | NPC1 (0.40) | L3MBTL1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL18744469 | 0.75 | ESR1 (0.42) | L3MBTL1MEN1KMT2ANPC1RECQL | |
| SCHEMBL22404254 | 0.75 | HCAR3 (0.56) | L3MBTL1TLR7MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012142329-A1 | COMPOSITIONS AND THERAPEUTIC USES OF IKK-RELATED KINASE EPSILON AND TANKBINDING KINASE 1 INHIBITORS | MYREXIS, INC. (US) | 2012-10-18 | — | — | WO | disclosed |