SCHEMBL13467299

SCHEMBL13467299

CCCCCCCCCCCCCCCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NC(C)C)C(C)C)C(C)C)C(C)C

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.61
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
MAPK1 P28482 1/20 0.61
PLA2G2A P14555 1/20 0.44
PLA2G5 P39877 1/20 0.44
DNM1 Q05193 1/20 0.44
CTSL P07711 1/20 0.42
PLA2G10 O15496 2/20 0.42
NOD1 Q9Y239 1/20 0.41
PLA2G2C Q5R387 1/20 0.41
HSP90AA1 P07900 1/20 0.41
ASAH2 Q9NR71 1/20 0.41
CASP1 P29466 1/20 0.41
ALDH1A1 P00352 1/20 0.40
ASAH1 Q13510 1/20 0.40
ACER2 Q5QJU3 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15381911 1.00 FAAH (0.61) FAAHMEN1KMT2AMAPK1PLA2G2A
SCHEMBL13120987 0.90 FAAH (0.51) FAAHMEN1KMT2AMAPK1PLA2G2A
SCHEMBL10028943 0.90 FAAH (0.51) FAAHMEN1KMT2AMAPK1PLA2G2A
SCHEMBL13821695 0.90 FAAH (0.51) FAAHMEN1KMT2AMAPK1PLA2G2A
SCHEMBL13467397 0.90 FAAH (0.51) FAAHMEN1KMT2AMAPK1PLA2G2A
SCHEMBL19227333 0.87 FAAH (0.59) FAAHMEN1KMT2AMAPK1DNM1
SCHEMBL19227314 0.86 FAAH (0.58) FAAHMEN1KMT2AMAPK1DNM1
SCHEMBL27111229 0.86 FAAH (0.45) FAAHMEN1KMT2AMAPK1CASP1
SCHEMBL23948580 0.85 FAAH (0.56) FAAHMEN1KMT2AMAPK1PLA2G2A
SCHEMBL30018188 0.85 FAAH (0.62) FAAHMEN1KMT2AMAPK1PLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8580923-B2 Self-assembling peptide amphiphiles and related methods for growth factor delivery NORTHWESTERN UNIVERSITY (US) 2013-11-12 US disclosed
US-20120264912-A1 SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY NORTHWESTERN UNIVERSITY (US) 2012-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120264912-A1 SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY HDGF, HDGFL3, IAPP FAAH 3103/4885MEN1 987/4885KMT2A 4467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.