Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAG1 | P54619 | 1/20 | 0.47 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.47 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.47 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13467468 | 0.82 | NPC1 (0.48) | SLC29A1ADORA3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12579985 | 0.80 | PAX8 (0.51) | PRKAG1PRKAA1PRKAB1SLC29A1PAX8 | |
| SCHEMBL14713289 | 0.77 | ADORA3 (0.52) | PRKAG1PRKAA1PRKAB1SLC29A1ADORA3 | |
| SCHEMBL12579588 | 0.77 | ADORA3 (0.52) | PRKAG1PRKAA1PRKAB1SLC29A1ADORA3 | |
| SCHEMBL13467264 | 0.76 | AURKA (0.46) | SLC29A1PAX8ADORA3NPC1RAB9A | |
| SCHEMBL13467417 | 0.76 | NR2F2 (0.57) | SLC29A1PAX8ADORA3NPC1RAB9A | |
| SCHEMBL20626430 | 0.75 | SLC29A1 (0.41) | PRKAG1PRKAA1PRKAB1SLC29A1ADORA3 | |
| SCHEMBL12579587 | 0.75 | SLC29A1 (0.41) | PRKAG1PRKAA1PRKAB1SLC29A1ADORA3 | |
| SCHEMBL14713319 | 0.75 | SLC29A1 (0.41) | PRKAG1PRKAA1PRKAB1SLC29A1ADORA3 | |
| SCHEMBL22866575 | 0.74 | NT5E (0.59) | SLC29A1NPC1RAB9ASMN1; SMN2NR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2511283-A1 | N6-SUBSTITUTED ADENOSINE DERIVATIVES, N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2012-10-17 | — | — | EP | disclosed |