Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 6/20 | 0.49 |
| ▸ | RIN1 | Q13671 | 6/20 | 0.49 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13467239 | 0.91 | PRKAG1 (0.48) | ABL1RIN1NR2F2GALR3ALDH1A1 | |
| SCHEMBL13467488 | 0.85 | SLC29A1 (0.57) | ALDH1A1TP53CYP3A4TSHRALOX12 | |
| SCHEMBL14714120 | 0.82 | ADORA3 (0.68) | ALDH1A1LMNATP53CYP3A4TSHR | |
| SCHEMBL14714044 | 0.82 | ADORA3 (0.68) | ALDH1A1LMNATP53CYP3A4TSHR | |
| SCHEMBL14713405 | 0.82 | ADORA3 (0.68) | ALDH1A1LMNATP53CYP3A4TSHR | |
| SCHEMBL20626434 | 0.82 | ADORA3 (0.68) | ALDH1A1LMNATP53CYP3A4TSHR | |
| SCHEMBL20626435 | 0.82 | ADORA3 (0.68) | ALDH1A1LMNATP53CYP3A4TSHR | |
| SCHEMBL20626418 | 0.82 | ADORA3 (0.68) | ALDH1A1LMNATP53CYP3A4TSHR | |
| SCHEMBL20626420 | 0.82 | ADORA3 (0.68) | ALDH1A1LMNATP53CYP3A4TSHR | |
| SCHEMBL14713392 | 0.82 | ADORA3 (0.68) | ALDH1A1LMNATP53CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2511283-A1 | N6-SUBSTITUTED ADENOSINE DERIVATIVES, N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2012-10-17 | — | — | EP | disclosed |