Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.33 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23184184 | 0.94 | GPR3 (0.41) | GPR3MAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL23184309 | 0.94 | GPR3 (0.41) | GPR3MAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL22930728 | 0.92 | MAPT (0.47) | GPR3MAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL19760320 | 0.90 | MAPT (0.47) | GPR3MAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL18156881 | 0.90 | MAPT (0.48) | GPR3MAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL13467824 | 0.85 | ALDH1A1 (0.35) | GPR3MAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL13467817 | 0.85 | MAPT (0.42) | GPR3MAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL13467608 | 0.84 | ALDH1A1 (0.34) | GPR3MAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL23184307 | 0.83 | GPR3 (0.40) | GPR3MAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL23184192 | 0.83 | GPR3 (0.40) | GPR3MAPTALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140027757-A1 | NOVEL SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE HAVING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2014-01-30 | — | — | US | disclosed |
| US-20140027757-A1 | NOVEL SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE HAVING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2014-01-30 | — | — | US | disclosed |
| WO-2012141229-A1 | NOVEL SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE HAVING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2012-10-18 | — | — | WO | disclosed |