Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.79 |
| ▸ | KDR | P35968 | 20/20 | 0.79 |
| ▸ | IGF1R | P08069 | 19/20 | 0.70 |
| ▸ | MST1R | Q04912 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13467647 | 0.93 | MET (0.68) | METKDRIGF1RMST1R | |
| SCHEMBL13467869 | 0.91 | MET (0.68) | METKDRIGF1RMST1R | |
| SCHEMBL13467862 | 0.91 | MET (0.79) | METKDRIGF1RMST1R | |
| SCHEMBL13467625 | 0.90 | MET (0.79) | METKDRIGF1RMST1R | |
| SCHEMBL13467868 | 0.90 | MET (0.79) | METKDRIGF1RMST1R | |
| SCHEMBL13467609 | 0.90 | MET (0.79) | METKDRIGF1RMST1R | |
| SCHEMBL13467705 | 0.89 | MET (0.71) | METKDRIGF1RMST1R | |
| SCHEMBL198809 | 0.88 | MET (1.00) | METKDRIGF1RMST1R | |
| SCHEMBL13467880 | 0.85 | MET (0.67) | METKDRIGF1RMST1R | |
| SCHEMBL13467863 | 0.83 | MET (0.61) | METKDRIGF1RMST1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881976-B1 | SUBSTITUTED AMIDE DERIVATIVES AS PROTEIN KINASE INHIBITORS | AMGEN INC (US) | 2012-10-17 | — | — | EP | disclosed |