Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 4/20 | 0.70 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | MMP7 | P09237 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 3/20 | 0.37 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.36 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18427362 | 0.80 | IDH1 (0.64) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL23153390 | 0.80 | IDH1 (0.64) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL13024178 | 0.79 | IDH1 (0.62) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL13531433 | 0.78 | IDH1 (0.66) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL22852019 | 0.78 | IDH1 (0.66) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL19978233 | 0.78 | IDH1 (0.60) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL17770632 | 0.77 | IDH1 (0.59) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL13469336 | 0.77 | IDH1 (0.64) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL13469343 | 0.77 | IDH1 (0.64) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL38651963 | 0.77 | IDH1 (0.64) | IDH1MMP1MMP3MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018048879-A1 | METAL CHELATORS FOR IMAGING, THERAPEUTICS, AND BIOANALYSIS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-03-15 | — | — | WO | disclosed |
| US-20170298272-A1 | LIGAND-SENSITIZED LANTHANIDE NANOCRYSTALS AS ULTRAVIOLET DOWNCONVERTERS | ENERGY, UNITED STATES DEPARTMENT OF | 2017-10-19 | — | — | US | disclosed |
| US-9556122-B2 | Luminescent 1-hydroxy-2-pyridinone chelates of lanthanides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-01-31 | — | — | US | disclosed |
| US-9556122-B2 | Luminescent 1-hydroxy-2-pyridinone chelates of lanthanides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-01-31 | — | — | US | disclosed |
| US-20140039169-A1 | LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2014-02-06 | — | — | US | disclosed |
| US-8557601-B2 | Luminescent 1-hydroxy-2-pyridinone chelates of lanthanides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-10-15 | — | — | US | disclosed |
| EP-2511266-A1 | Luminescent 1-Hydroxy-2-Pyridinone Chelates of Lanthanides | The Regents of The University of California (US) | 2012-10-17 | — | — | EP | disclosed |
| US-20100015725-A1 | LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-01-21 | — | — | US | disclosed |
| WO-2008008797-A2 | LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140039169-A1 | LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES | PLPBP, HPD, LASP1 | IDH1 25/4885MMP1 945/4885MMP3 1614/4885 |
| US-20100015725-A1 | LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES | PLPBP, HPD, LASP1 | IDH1 25/4885MMP1 945/4885MMP3 1614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.