SCHEMBL13469345

SCHEMBL13469345

CCc1nccn1C1CCCCO1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.42
YTHDC1 Q96MU7 1/20 0.39
KMT2A Q03164 4/20 0.38
MEN1 O00255 3/20 0.38
ALDH1A1 P00352 3/20 0.36
TP53 P04637 1/20 0.36
CYP2C9 P11712 1/20 0.36
NFKB1 P19838 1/20 0.36
MAPK1 P28482 1/20 0.36
HSD17B10 Q99714 1/20 0.36
APEX1 P27695 1/20 0.36
PI4KA P42356 1/20 0.36
BLM P54132 1/20 0.36
ADCY1 Q08828 1/20 0.36
PI4K2B Q8TCG2 1/20 0.36
PI4K2A Q9BTU6 1/20 0.36
PI4KB Q9UBF8 1/20 0.36
CYP4F2 P78329 2/20 0.36
CYP4A11 Q02928 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19949182 0.85 CYP2C19 (0.39) CYP2C19YTHDC1KMT2AMEN1ALDH1A1
SCHEMBL1485370 0.82 CYP2C19 (0.38) CYP2C19YTHDC1KMT2AMEN1ALDH1A1
SCHEMBL7904174 0.80 ALDH1A1 (0.40) CYP2C19YTHDC1KMT2AMEN1ALDH1A1
SCHEMBL1333153 0.80 ALDH1A1 (0.40) CYP2C19YTHDC1KMT2AMEN1ALDH1A1
Hydrochloric Acid SCHEMBL3980796 0.79 ALDH1A1 (0.39) CYP2C19YTHDC1KMT2AMEN1ALDH1A1
SCHEMBL6044670 0.76 CYP2C19 (0.42) CYP2C19YTHDC1KMT2AMEN1ALDH1A1
SCHEMBL15614521 0.76 CYP2C19 (0.42) CYP2C19YTHDC1KMT2AMEN1ALDH1A1
SCHEMBL28391787 0.76 F10 (0.39) KMT2AALDH1A1TP53PI4KAPI4K2B
SCHEMBL1564295 0.73 P2RY12 (0.40) CYP2C19KMT2AMEN1ALDH1A1TP53
SCHEMBL20851567 0.73 F10 (0.41) CYP2C19ALDH1A1NFKB1MAPK1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012139891-A1 SUBSTITUTED VINYL AND ALKINYL CYCLOHEXENOLS AS ACTIVE AGENTS AGAINST ABIOTIC STRESS IN PLANTS BAYER CROPSCIENCE AG (DE) 2012-10-18 WO disclosed