Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15614521 | 0.80 | CYP2C19 (0.42) | CYP2C19YTHDC1KMT2AALDH1A1MEN1 | |
| SCHEMBL13527817 | 0.77 | CYP2C19 (0.38) | CYP2C19YTHDC1KMT2AALDH1A1MEN1 | |
| SCHEMBL13469345 | 0.76 | CYP2C19 (0.42) | CYP2C19YTHDC1KMT2AALDH1A1MEN1 | |
| SCHEMBL19949182 | 0.76 | CYP2C19 (0.39) | CYP2C19YTHDC1KMT2AALDH1A1MEN1 | |
| SCHEMBL13527818 | 0.76 | CYP2C19 (0.39) | CYP2C19YTHDC1KMT2AALDH1A1MEN1 | |
| SCHEMBL15543652 | 0.74 | LMNA (0.37) | KMT2AALDH1A1MEN1TP53PI4KA | |
| SCHEMBL10805867 | 0.74 | CYP2C19 (0.38) | CYP2C19YTHDC1KMT2AALDH1A1MEN1 | |
| SCHEMBL1485370 | 0.71 | CYP2C19 (0.38) | CYP2C19YTHDC1KMT2AALDH1A1MEN1 | |
| SCHEMBL1564274 | 0.71 | KMT2A (0.40) | CYP2C19YTHDC1KMT2AALDH1A1MEN1 | |
| SCHEMBL7904174 | 0.71 | ALDH1A1 (0.40) | CYP2C19YTHDC1KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8715635-B2 | Frictionless molecular rotary motors | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2014-05-06 | — | — | US | disclosed |
| US-8715635-B2 | Frictionless molecular rotary motors | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2014-05-06 | — | — | US | disclosed |
| US-20100016610-A1 | FRICTIONLESS MOLECULAR ROTARY MOTORS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2010-01-21 | — | — | US | disclosed |
| US-20100016610-A1 | FRICTIONLESS MOLECULAR ROTARY MOTORS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2010-01-21 | — | — | US | disclosed |
| WO-2008096360-A2 | FRICTIONLESS MOLECULAR ROTARY MOTORS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2008-08-14 | — | — | WO | disclosed |
| US-20060100196-A1 | Substituted amines for the treatment of alzheimer's disease | ELAN PHARMACEUTICALS, INC. | 2006-05-11 | — | — | US | disclosed |
| EP-1430032-A2 | SUBSTITUTED AMIDES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | Elan Pharmaceuticals, Inc. (US) | 2004-06-23 | — | — | EP | disclosed |
| WO-2003027068-A2 | SUBSTITUTED AMINES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | ELAN PHARMACEUTICALS, INC. (US) | 2003-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100196-A1 | Substituted amines for the treatment of alzheimer's disease | BACE1, APP, BACE2 | CYP2C19 801/4885YTHDC1 4543/4885KMT2A 1649/4885 |
| US-20100016610-A1 | FRICTIONLESS MOLECULAR ROTARY MOTORS | DYNLL2, ATXN2L, DYNLL1 | CYP2C19 4658/4885YTHDC1 4285/4885KMT2A 1032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.