Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 2/20 | 0.31 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.30 |
| ▸ | ACLY | P53396 | 1/20 | 0.30 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9372723 | 0.85 | TDP1 (0.46) | TDP1SLC22A6SMN1; SMN2ALDH1A1HMGCR | |
| SCHEMBL9474321 | 0.83 | TDP1 (0.43) | TDP1SLC22A6SMN1; SMN2ALDH1A1HMGCR | |
| SCHEMBL10520915 | 0.73 | TDP1 (0.43) | TDP1SLC22A6SMN1; SMN2ALDH1A1HMGCR | |
| Ammonia Solution, Strong SCHEMBL11416138 | 0.71 | LMNA (0.43) | TDP1SLC22A6ALDH1A1ADRA1ACYP2D6 | |
| SCHEMBL10520908 | 0.69 | SLC22A6 (0.46) | TDP1SLC22A6SMN1; SMN2ALDH1A1HMGCR | |
| SCHEMBL750130 | 0.67 | TDP1 (0.42) | TDP1SLC22A6SMN1; SMN2ALDH1A1HMGCR | |
| SCHEMBL7999396 | 0.65 | TDP1 (0.40) | TDP1SLC22A6SMN1; SMN2ALDH1A1HMGCR | |
| SCHEMBL396503 | 0.65 | TDP1 (0.40) | TDP1SLC22A6SMN1; SMN2ALDH1A1HMGCR | |
| SCHEMBL10902910 | 0.65 | TDP1 (0.40) | TDP1SLC22A6SMN1; SMN2ALDH1A1HMGCR | |
| SCHEMBL3336391 | 0.64 | TDP1 (0.39) | TDP1SLC22A6SMN1; SMN2ALDH1A1HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120264961-A1 | FE3O4-M(AU-LIKE)-NANOPARTICLES FOR ANTIBODY-CONSERVING TARGET-SPECIFIC PLATIN DELIVERY | BROWN UNIVERSITY (US) | 2012-10-18 | — | — | US | disclosed |