SCHEMBL750130

SCHEMBL750130

NC(CC(=O)O)C(CC(=O)O)(CC(=O)O)CC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.42
SLC22A6 Q4U2R8 1/20 0.38
GABRR1 P24046 2/20 0.37
LMNA P02545 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HMGCR P04035 1/20 0.35
CHRM1 P11229 1/20 0.35
TBXA2R P21731 1/20 0.35
ADRA1A P35348 1/20 0.35
KDM4E B2RXH2 1/20 0.34
CYP2D6 P10635 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
CPT2 P23786 1/20 0.32
ACLY P53396 1/20 0.32
CACNB3 P54284 1/20 0.31
CACNA2D1 P54289 1/20 0.31
CACNA1C Q13936 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7999396 0.98 TDP1 (0.40) TDP1SLC22A6GABRR1LMNASMN1; SMN2
SCHEMBL396503 0.98 TDP1 (0.40) TDP1SLC22A6GABRR1LMNASMN1; SMN2
SCHEMBL465794 0.78 TDP1 (0.40) TDP1SLC22A6GABRR1LMNASMN1; SMN2
SCHEMBL3336391 0.76 TDP1 (0.39) TDP1SLC22A6GABRR1LMNASMN1; SMN2
Hydrochloric Acid SCHEMBL28132580 0.76 SLC22A6 (0.35) TDP1SLC22A6GABRR1LMNASMN1; SMN2
SCHEMBL271763 0.76 TDP1 (0.39) TDP1SLC22A6GABRR1LMNASMN1; SMN2
SCHEMBL9805121 0.75 TDP1 (0.37) TDP1SLC22A6GABRR1LMNASMN1; SMN2
Ammonia Solution, Strong SCHEMBL10701836 0.75 TDP1 (0.42) TDP1SLC22A6GABRR1LMNASMN1; SMN2
SCHEMBL9372723 0.74 TDP1 (0.46) TDP1SLC22A6GABRR1LMNASMN1; SMN2
SCHEMBL28726922 0.73 SLC22A6 (0.37) TDP1SLC22A6GABRR1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113874476-A Catalyst for reactivation hydrotreating for sulfur reduction 赢创运营有限公司 2021-12-31 CN disclosed
US-20140216478-A1 MULTILAYERED NONWOVEN FABRIC WITH ANTI-ALLERGIC EFFECT 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-08-07 US disclosed
EP-2721208-A2 MULTILAYERED NONWOVEN FABRIC WITH ANTI-ALLERGIC EFFECT 3M Innovative Properties Company (US) 2014-04-23 EP disclosed
WO-2012177648-A2 MULTILAYERED NONWOVEN FABRIC WITH ANTI-ALLERGIC EFFECT 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-12-27 WO disclosed
US-20120264942-A1 METHOD FOR SCREENING OSTEOPONTIN INHIBITOR AND INHIBITOR OBTAINED FROM THE METHOD INNOPHARMASCREEN, INC. (KR) 2012-10-18 US disclosed
EP-2431738-A1 METHOD FOR SCREENING OSTEOPONTIN INHIBITOR AND INHIBITOR PREPARED THEREBY Innopharmascreen Inc. (KR) 2012-03-21 EP disclosed
EP-1638546-A1 USE OF ALPHA-KETOGLUTARIC ACID FOR THE TREATMENT OF MALNUTRITION OR HIGH PLASMA GLUCOSE CONDITION Essentys AB (SE) 2006-03-29 EP disclosed
WO-2005002567-A1 USE OF ALPHA-KETOGLUTARIC ACID FOR THE TREATMENT OF MALNUTRITION OR HIGH PLASMA GLUCOSE CONDITION ESSENTYS AB (SE) 2005-01-13 WO disclosed
EP-0921726-A4 STOMACH-ACTION MOLLUSCICIDES YOUNG COLIN LESLIE (AU) 2000-06-21 EP disclosed
US-5985508-A SILVER HALIDE EMULSIONS ON SUPPORTS WITH COLLOID LAYERS, GOLD SULFUR SENSITIZATION AND TREATMENT WITH HYDRAZIDES FUJI PHOTO FILM CO., LTD. (JP) 1999-11-16 US disclosed
EP-0921726-A1 STOMACH-ACTION MOLLUSCICIDES Young, Colin Leslie (AU) 1999-06-16 EP disclosed
US-5888694-A MATERIAL CONTAINING COMPOUND HAVING ADSORPTION ACCELERATING GROUP AND QUATERNIZED NITROGEN-CONTAINING HETEROCYCLIC RING;FORMING HIGH CONTRAST IMAGES FUJI PHOTO FILM CO., LTD. (JP) 1999-03-30 US disclosed
US-5759758-A Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1998-06-02 US disclosed
WO-1997026789-A1 STOMACH-ACTION MOLLUSCICIDES YOUNG COLIN LESLIE (AU) 1997-07-31 WO disclosed
US-5356760-A Silver chlorobromide emulsion containing resorcinol-based or aminophenol-based coupler, gelatin in specifed coating weight, on support KONICA CORPORATION (JP) 1994-10-18 US disclosed
EP-0568777-A1 Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1993-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120264942-A1 METHOD FOR SCREENING OSTEOPONTIN INHIBITOR AND INHIBITOR OBTAINED FROM THE METHOD SOST, ACP3, PTH1R TDP1 3404/4885SLC22A6 2165/4885GABRR1 4284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.