Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 14/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19944871 | 1.00 | CYP2D6 (0.43) | CYP2D6CTSKCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19944668 | 0.88 | CTSK (0.43) | CTSKCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL19944461 | 0.87 | CYP2D6 (0.33) | CYP2D6CTSKCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20349139 | 0.80 | CYP2D6 (0.35) | CYP2D6CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL15459310 | 0.79 | HDAC3 (0.34) | CYP2D6CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL9961219 | 0.78 | CYP2D6 (0.44) | CYP2D6CTSK | |
| SCHEMBL9961170 | 0.78 | CTSK (0.43) | CYP2D6CTSKCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9961200 | 0.78 | CTSK (0.43) | CYP2D6CTSKCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13471117 | 0.76 | CYP2D6 (0.45) | CYP2D6CTSKCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7884932 | 0.76 | CYP2D6 (0.45) | CYP2D6CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10975119-B2 | Selective cysteine protease inhibitors and uses thereof | GENESIS TECHNOLOGIES LIMITED (BB) | 2021-04-13 | — | — | US | disclosed |
| US-20180186833-A1 | SELECTIVE CYSTEINE PROTEASE INHIBITORS AND USES THEREOF | GENESIS TECH LIMITED (BB) | 2018-07-05 | — | — | US | disclosed |
| US-20180186833-A1 | SELECTIVE CYSTEINE PROTEASE INHIBITORS AND USES THEREOF | GENESIS TECH LIMITED (BB) | 2018-07-05 | — | — | US | disclosed |
| US-9944674-B2 | Selective cysteine protease inhibitors and uses thereof | GENESIS TECHNOLOGIES LIMITED (BB) | 2018-04-17 | — | — | US | disclosed |
| US-9944674-B2 | Selective cysteine protease inhibitors and uses thereof | GENESIS TECHNOLOGIES LIMITED (BB) | 2018-04-17 | — | — | US | disclosed |
| US-20140038903-A1 | Selective Cysteine Protease Inhibitors and Uses Thereof | NEW WORLD LABORATORIES, INC. (CA) | 2014-02-06 | — | — | US | disclosed |
| US-20140038903-A1 | Selective Cysteine Protease Inhibitors and Uses Thereof | NEW WORLD LABORATORIES, INC. (CA) | 2014-02-06 | — | — | US | disclosed |
| WO-2012140500-A1 | SELECTIVE CYSTEINE PROTEASE INHIBITORS AND USES THEREOF | NEW WORLD LABORATORIES, INC. (CA) | 2012-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140038903-A1 | Selective Cysteine Protease Inhibitors and Uses Thereof | SERPINB1, SERPINE1, CASP5 | CYP2D6 1585/4885CTSK 138/4885CYP1A2 2156/4885 |
| US-20180186833-A1 | SELECTIVE CYSTEINE PROTEASE INHIBITORS AND USES THEREOF | SERPINB1, SERPINE1, CASP5 | CYP2D6 1585/4885CTSK 138/4885CYP1A2 2156/4885 |
| US-10975119-B2 | Selective cysteine protease inhibitors and uses thereof | SERPINB1, SERPINE1, CASP5 | CYP2D6 1568/4885CTSK 128/4885CYP1A2 2138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.