Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 11/20 | 0.84 |
| ▸ | KDR | P35968 | 4/20 | 0.81 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.79 |
| ▸ | GSK3B | P49841 | 2/20 | 0.79 |
| ▸ | ARAF | P10398 | 2/20 | 0.79 |
| ▸ | BRAF | P15056 | 2/20 | 0.79 |
| ▸ | RET | P07949 | 2/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.79 |
| ▸ | PLK4 | O00444 | 1/20 | 0.79 |
| ▸ | CIT | O14578 | 1/20 | 0.79 |
| ▸ | AURKA | O14965 | 1/20 | 0.79 |
| ▸ | MUSK | O15146 | 1/20 | 0.79 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.79 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.79 |
| ▸ | MLNR | O43193 | 1/20 | 0.79 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.79 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.79 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.79 |
| ▸ | PDE6D | O43924 | 1/20 | 0.79 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2480623 | 0.93 | RAF1 (0.84) | RAF1KDRPDGFRBGSK3BARAF | |
| SCHEMBL13471762 | 0.93 | RAF1 (0.84) | RAF1KDRPDGFRBGSK3BARAF | |
| SCHEMBL3707691 | 0.92 | RAF1 (0.83) | RAF1KDRPDGFRBGSK3BARAF | |
| SCHEMBL937568 | 0.92 | RAF1 (1.00) | RAF1KDRPDGFRBGSK3BARAF | |
| SCHEMBL3407760 | 0.90 | KDR (0.84) | RAF1KDRPDGFRBGSK3BARAF | |
| SCHEMBL14481765 | 0.90 | RAF1 (0.86) | RAF1KDRPDGFRBGSK3BARAF | |
| SCHEMBL4737847 | 0.89 | KDR (1.00) | RAF1KDRPDGFRBGSK3BARAF | |
| SCHEMBL22473654 | 0.89 | RAF1 (0.82) | RAF1KDRPDGFRBGSK3BARAF | |
| SCHEMBL22001800 | 0.89 | RAF1 (0.82) | RAF1KDRPDGFRBGSK3BARAF | |
| SCHEMBL20909069 | 0.89 | RAF1 (0.82) | RAF1KDRPDGFRBGSK3BARAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120264789-A1 | POLYMORPHS OF SORAFENIB ACID ADDITION SALTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120264789-A1 | POLYMORPHS OF SORAFENIB ACID ADDITION SALTS | TP53, HCCS, SF3B5 | RAF1 133/4885KDR 152/4885PDGFRB 728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.