SCHEMBL22473654

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20573690	0.91	RAF1 (0.77)	RAF1KDRPDGFRBBRAFRET
	SCHEMBL937568	0.90	RAF1 (1.00)	RAF1KDRPDGFRBBRAFRET
	SCHEMBL20573976	0.89	GSK3B (0.78)	RAF1KDRPDGFRBBRAFRET
	SCHEMBL13471761	0.89	RAF1 (0.84)	RAF1KDRPDGFRBBRAFRET
	SCHEMBL13471762	0.89	RAF1 (0.84)	RAF1KDRPDGFRBBRAFRET
	SCHEMBL2480623	0.89	RAF1 (0.84)	RAF1KDRPDGFRBBRAFRET
	SCHEMBL14481765	0.89	RAF1 (0.86)	RAF1KDRPDGFRBBRAFRET
	SCHEMBL3707691	0.88	RAF1 (0.83)	RAF1KDRPDGFRBBRAFRET
	SCHEMBL22001800	0.88	RAF1 (0.82)	RAF1KDRPDGFRBBRAFRET
	SCHEMBL20909069	0.88	RAF1 (0.82)	RAF1KDRPDGFRBBRAFRET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.