Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 11/20 | 0.77 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.76 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.76 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.76 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.76 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.76 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.76 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.76 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.76 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.76 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.76 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.76 |
| ▸ | GSK3B | P49841 | 2/20 | 0.76 |
| ▸ | KDR | P35968 | 5/20 | 0.74 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.74 |
| ▸ | ARAF | P10398 | 2/20 | 0.74 |
| ▸ | BRAF | P15056 | 2/20 | 0.74 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | PLK4 | O00444 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3707691 | 0.90 | RAF1 (0.83) | RAF1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22001800 | 0.88 | RAF1 (0.82) | RAF1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2480623 | 0.88 | RAF1 (0.84) | RAF1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13471761 | 0.88 | RAF1 (0.84) | RAF1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13471762 | 0.88 | RAF1 (0.84) | RAF1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL14479155 | 0.87 | KDR (0.73) | RAF1HDAC3HDAC4HDAC1HDAC7 | |
| Sorafenib SCHEMBL2045626 | 0.87 | RAF1 (0.88) | RAF1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20386909 | 0.87 | RAF1 (0.81) | RAF1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL937568 | 0.87 | RAF1 (1.00) | RAF1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21973628 | 0.87 | RAF1 (0.82) | RAF1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120264789-A1 | POLYMORPHS OF SORAFENIB ACID ADDITION SALTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120264789-A1 | POLYMORPHS OF SORAFENIB ACID ADDITION SALTS | TP53, HCCS, SF3B5 | RAF1 133/4885HDAC3 1229/4885HDAC4 1065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.