Methane

Methane

SCHEMBL134744

C.C.C.C.C.C.[SiH3]O[Si](O[SiH3])(O[SiH3])c1ccccc1

nearest known ligand 0.31

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Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
LTA4H P09960 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28427359 0.97 ESR1 (0.32) ESR1ESR2LTA4HTSHR
Methane SCHEMBL2931201 0.78 ESR1 (0.31) ESR1ESR2LTA4HTSHR
SCHEMBL9259574 0.76 ORAI1 (0.31) ESR1ESR2TSHR
SCHEMBL913097 0.74 ESR1 (0.32) ESR1ESR2LTA4HTSHR
SCHEMBL9900193 0.74 ESR1 (0.32) ESR1ESR2LTA4HTSHR
SCHEMBL9004199 0.74 POLB (0.37) ESR1ESR2LTA4HTSHR
Methane SCHEMBL11653540 0.74 ESR1 (0.33) ESR1ESR2
SCHEMBL9771825 0.74 POLB (0.37) ESR1ESR2LTA4HTSHR
SCHEMBL31318429 0.70 MAPK1 (0.34) ESR1ESR2
SCHEMBL3882939 0.70 TSHR (0.30) ESR1ESR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 354 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3792318-A1 COMPOSITE OF PHASE CHANGE MATERIAL-CONTAINING MICROCAPSULES AND SILICA, PREPARATION METHOD THEREFOR, AND NON-FLAMMABLE BINDER COMPOSITION COMPRISING SAME BA Energy Co., Ltd. (KR) 2021-03-17 EP claimed
US-7615387-B2 Addition curing silicone composition capable of producing a cured product with excellent crack resistance SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-11-10 US claimed
EP-0672745-B1 Electrorheological gels and method for preparation DOW CORNING (US) 1998-02-25 EP claimed
US-5665471-A Fiber treatment compositions and methods for the preparation thereof DOW CORNING CORPORATION (US) 1997-09-09 US claimed
US-5527476-A RHODIUM CATALYST FOR CROSSLINKING METHYLHYDROGENSILOXANES IN TREATING FIBERS OR FABRICS DOW CORNING CORPORATION (US) 1996-06-18 US claimed
US-5514418-A UNSATURATED ACETATE, ALKYLHYDROGENSILOXANE, METAL CATALYST, TEXTILES DOW CORNING CORPORATION (US) 1996-05-07 US claimed
EP-0672745-A2 Electrorheological gels and method for preparation DOW CORNING CORPORATION (US) 1995-09-20 EP claimed
EP-0661399-A1 Catalyst compositions and methods for the preparation thereof DOW CORNING CORPORATION (US) 1995-07-05 EP claimed
EP-0661400-A1 Fiber treatment compositions and methods for the preparation thereof DOW CORNING CORPORATION (US) 1995-07-05 EP claimed
EP-0661398-A1 Fiber treatment compositions containing organofunctional siloxanes and methods for the preparation thereof DOW CORNING CORPORATION (US) 1995-07-05 EP claimed
US-5413724-A Treatment for waterproofing, softness, compression resistance of fabrics and fibers using unsaturated acetates and hydrogen siloxanes DOW CORNING CORPORATION (US) 1995-05-09 US claimed
US-5412006-A Electrorheological cels and a method for the preparation thereof DOW CORNING CORPORATION (US) 1995-05-02 US claimed
US-5409620-A Fiber treatment compositions containing organofunctional siloxanes and methods for the preparation thereof DOW CORNING CORPORATION (US) 1995-04-25 US claimed
US-12037481-B2 Curable organopolysiloxane composition for forming films, and method for producing organopolysiloxane cured film DOW TORAY CO., LTD. (JP) 2024-07-16 US disclosed
EP-3892687-B1 CURABLE ORGANOPOLYSILOXANE COMPOSITION FOR FORMING FILMS, AND METHOD FOR PRODUCING ORGANOPOLYSILOXANE CURED FILM DOW TORAY CO LTD (JP) 2024-06-26 EP disclosed
WO-2024116829-A1 ADDITION-CURABLE LIQUID SILICONE RUBBER COMPOSITION FOR AIRBAGS, AND AIRBAG 信越化学工業株式会社 2024-06-06 WO disclosed
US-4230815-A Silicon-containing polybutadiene derivatives and method for the preparation thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 1980-10-28 US disclosed
US-4045390-A DIORGANOPOLYSILOXANE BLOCK POLYMER, CROSSLINKING AGENT, SILICA FILLER, PLATINUM CATALYST SHIN-ETSU CHEMICAL CO., LTD. (JA) 1977-08-30 US disclosed
US-3996195-A POLYSILOXANES, PLATINUM CATALYSTS SHINETSU CHEMICAL COMPANY (JA) 1976-12-07 US disclosed
US-3974122-A Heat-curable silicone resin compositions SHIN-ETSU CHEMICAL CO., LTD. (JA) 1976-08-10 US disclosed