SCHEMBL913097

SCHEMBL913097

[SiH3]O[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
LTA4H P09960 1/20 0.32
TSHR P16473 1/20 0.32
DUT P33316 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9117412 0.79 TSHR (0.36) ESR1TSHRALDH1A1
SCHEMBL2675596 0.78
SCHEMBL11113450 0.77 ALDH1A1 (0.37) ESR1ESR2LTA4HTSHRDUT
SCHEMBL9900193 0.77 ESR1 (0.32) ESR1ESR2LTA4HTSHRALDH1A1
SCHEMBL28427359 0.77 ESR1 (0.32) ESR1ESR2LTA4HTSHRALDH1A1
SCHEMBL335769 0.75 TSHR (0.35) ESR1ESR2LTA4HTSHRDUT
SCHEMBL7727762 0.75 TSHR (0.35) ESR1ESR2LTA4HTSHRDUT
Methane SCHEMBL2931201 0.74 ESR1 (0.31) ESR1ESR2LTA4HTSHR
Methane SCHEMBL134744 0.74 ESR1 (0.31) ESR1ESR2LTA4HTSHR
SCHEMBL28705381 0.74 ESR1 (0.33) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3830196-A1 SURFACE TREATMENT COMPOSITIONS AND METHODS FUJIFILM Electronic Materials U.S.A, Inc. (US) 2021-06-09 EP claimed
CN-110078927-B Heat-resistant boron-containing hydrogen-containing silicone oil and preparation method thereof 合肥工业大学 2021-04-20 CN claimed
EP-3735325-A1 SURFACE TREATMENT COMPOSITIONS AND METHODS FUJIFILM Electronic Materials U.S.A, Inc. (US) 2020-11-11 EP claimed
WO-2020028214-A1 SURFACE TREATMENT COMPOSITIONS AND METHODS FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2020-02-06 WO claimed
WO-2019135901-A1 SURFACE TREATMENT COMPOSITIONS AND METHODS FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2019-07-11 WO claimed
US-20070203317-A1 HIGH REFRACTIVE INDEX FLEXIBLE SILICONE OPHTEC B.V. (NL) 2007-08-30 US claimed
US-7217778-B2 High refractive index flexible silicone OPHTEC B.V. (NL) 2007-05-15 US claimed
EP-1472305-A1 HIGH REFRACTIVE INDEX FLEXIBLE SILICONE Ophtec B.V. (NL) 2004-11-03 EP claimed
US-20030162929-A1 High refractive index flexible silicone OPHTEC B.V. (NL) 2003-08-28 US claimed
WO-2003066707-A1 HIGH REFRACTIVE INDEX FLEXIBLE SILICONE OPHTEC B.V. (NL) 2003-08-14 WO claimed
EP-1334991-A1 High refractive index flexible silicone Ophtec B.V. (NL) 2003-08-13 EP claimed
CN-110325591-B Rubber composition and crosslinked rubber 日本瑞翁株式会社 2024-07-09 CN disclosed
CN-112368331-B Ring-opened copolymer composition 日本瑞翁株式会社 2023-05-23 CN disclosed
CN-115819773-A Preparation method of high-temperature-resistant benzyl silicone oil with narrow molecular weight distribution 浙江开化合成材料有限公司 2023-03-21 CN disclosed
CN-115668459-A Surface treatment method for semiconductor substrate and surface treatment agent composition 中央硝子株式会社 2023-01-31 CN disclosed
US-4198131-A Silicone resin optical devices DOW CORNING CORPORATION (US) 1980-04-15 US disclosed
US-4147707-A MOLDING MATERIALS BAYER AKTIENGESELLSCHAFT (DE) 1979-04-03 US disclosed
US-4077822-A Splice for use during the thermal stabilization of a flat multifilament band of an acrylic fibrous material comprising at least two segments CELANESE CORPORATION (US) 1978-03-07 US disclosed
US-3974122-A Heat-curable silicone resin compositions SHIN-ETSU CHEMICAL CO., LTD. (JA) 1976-08-10 US disclosed
US-3962160-A NOVEL ORGANOFUNCTIONAL (KETOXIMINO) SILANES AND ROOM TEMPERATURE, VULCANIZABLE COMPOSITIONS CONTAINING THE SAME GENERAL ELECTRIC COMPANY (US) 1976-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070203317-A1 HIGH REFRACTIVE INDEX FLEXIBLE SILICONE MACF1, SMCHD1, RPIA ESR1 3116/4885ESR2 2868/4885LTA4H 1025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.