SCHEMBL9259574

SCHEMBL9259574

[SiH3]O[Si](Cl)(c1ccccc1)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ORAI1 Q96D31 1/20 0.31
ORAI2 Q96SN7 1/20 0.31
ORAI3 Q9BRQ5 1/20 0.31
TRPV6 Q9H1D0 1/20 0.31
TSHR P16473 1/20 0.30
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL297042 0.78 TSHR (0.33) ORAI1ORAI2ORAI3TRPV6TSHR
SCHEMBL28427359 0.78 ESR1 (0.32) TSHRESR1ESR2
Methane SCHEMBL134744 0.76 ESR1 (0.31) TSHRESR1ESR2
SCHEMBL11034567 0.75 ESR1 (0.37) ESR1ESR2
SCHEMBL10824434 0.74 CA4 (0.38) ORAI1ORAI2ORAI3TRPV6TSHR
SCHEMBL913097 0.72 ESR1 (0.32) TSHRESR1ESR2
SCHEMBL9900193 0.72 ESR1 (0.32) TSHRESR1ESR2
Hydrochloric Acid SCHEMBL11273196 0.72
SCHEMBL13853170 0.72 ALDH1A1 (0.32)
SCHEMBL4283846 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7292158-A None JP disclosed
JP-H07292158-A TIRE SIDE WALL RUBBER COMPOSITION SUMITOMO RUBBER IND LTD 1995-11-07 JP disclosed