Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.50 |
| ▸ | PGR | P06401 | 5/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 11/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13770648 | 0.82 | AR (0.44) | ARPGRNR3C2CYP19A1SLC22A1 | |
| SCHEMBL14099451 | 0.80 | AR (0.49) | ARPGRNR3C2CYP19A1SLC22A1 | |
| SCHEMBL13474778 | 0.79 | AR (0.45) | ARPGRNR3C2SLC22A1ALDH1A1 | |
| SCHEMBL13769017 | 0.78 | AR (0.44) | ARPGRNR3C2LMNA | |
| SCHEMBL9138228 | 0.77 | AR (0.53) | ARPGRNR3C2CYP19A1SLC22A1 | |
| SCHEMBL9138223 | 0.77 | AR (0.53) | ARPGRNR3C2CYP19A1SLC22A1 | |
| SCHEMBL13474752 | 0.75 | AR (0.49) | ARPGRNR3C2CYP19A1SLC22A1 | |
| SCHEMBL13770649 | 0.74 | AR (0.44) | ARPGRNR3C2CYP19A1SLC22A1 | |
| SCHEMBL13809834 | 0.74 | AR (0.58) | ARPGRNR3C2CYP19A1 | |
| SCHEMBL1656805 | 0.74 | AR (0.58) | ARPGRNR3C2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238147-B1 | 17-(1'-PROPENYL)-17-3'-OXIDOESTRA-4-EN-3-ONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER IP GMBH (DE) | 2012-10-24 | — | — | EP | disclosed |