Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.44 |
| ▸ | PGR | P06401 | 4/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.30 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13474778 | 0.89 | AR (0.45) | ARPGRNR3C2LMNAESR1 | |
| SCHEMBL13770129 | 0.78 | AR (0.46) | ARPGRNR3C2 | |
| SCHEMBL13769023 | 0.78 | PGR (0.43) | ARPGRNR3C2LMNAMAPT | |
| SCHEMBL13474796 | 0.78 | AR (0.50) | ARPGRNR3C2LMNA | |
| SCHEMBL13770648 | 0.74 | AR (0.44) | ARPGRNR3C2 | |
| SCHEMBL13797697 | 0.73 | AR (0.44) | ARPGRNR3C2LMNAESR1 | |
| SCHEMBL13797499 | 0.72 | AR (0.45) | ARPGRNR3C2 | |
| SCHEMBL13768996 | 0.72 | AR (0.43) | ARPGRNR3C2LMNAESR1 | |
| SCHEMBL3766911 | 0.71 | AR (0.51) | ARPGRNR3C2LMNAESR1 | |
| SCHEMBL6841944 | 0.69 | AR (0.55) | ARPGRNR3C2LMNAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083266-A1 | 17-HYDROXY-19-NOR-21-CARBOXYLIC ACID-STEROID γ-LACTONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING THE DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |