Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.49 |
| ▸ | PGR | P06401 | 3/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2833823 | 0.88 | AR (0.51) | ARPGRNR3C2LMNAMAPT | |
| SCHEMBL4261966 | 0.82 | AR (0.50) | ARPGRNR3C2LMNAMAPT | |
| SCHEMBL13216960 | 0.82 | AR (0.48) | ARPGRNR3C2LMNAMAPT | |
| SCHEMBL7703808 | 0.82 | SHBG (0.59) | ARPGRNR3C2LMNAMAPT | |
| SCHEMBL2832958 | 0.82 | SHBG (0.59) | ARPGRNR3C2LMNAMAPT | |
| SCHEMBL12638972 | 0.80 | AR (0.56) | ARPGRNR3C2SERPINA6ALDH1A1 | |
| SCHEMBL13474816 | 0.79 | AR (0.55) | ARPGRNR3C2LMNAMAPT | |
| SCHEMBL2953448 | 0.78 | AR (0.46) | ARPGRNR3C2LMNAMAPT | |
| SCHEMBL23383533 | 0.77 | SERPINA6 (0.61) | ARPGRNR3C2LMNAMAPT | |
| SCHEMBL10089012 | 0.77 | AR (0.55) | ARPGRNR3C2SERPINA6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238147-B1 | 17-(1'-PROPENYL)-17-3'-OXIDOESTRA-4-EN-3-ONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER IP GMBH (DE) | 2012-10-24 | — | — | EP | disclosed |