Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 11/20 | 0.50 |
| ▸ | PGR | P06401 | 11/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13770298 | 0.81 | AR (0.52) | ARPGRCYP19A1NR3C2 | |
| SCHEMBL13474804 | 0.80 | AR (0.54) | ARPGRCYP19A1NR3C2 | |
| SCHEMBL13770350 | 0.75 | CYP19A1 (0.54) | ARPGRCYP19A1NR3C2 | |
| SCHEMBL13770191 | 0.73 | PGR (0.50) | ARPGRCYP19A1NR3C2 | |
| SCHEMBL13770157 | 0.73 | PGR (0.35) | ARPGR | |
| SCHEMBL13769015 | 0.72 | PDK1 (0.33) | ARPGR | |
| SCHEMBL4107418 | 0.72 | PGR (0.54) | ARPGRCYP19A1NR3C2 | |
| SCHEMBL4101599 | 0.72 | PGR (0.54) | ARPGRCYP19A1NR3C2 | |
| SCHEMBL4212471 | 0.72 | PGR (0.61) | ARPGRCYP19A1NR3C2 | |
| SCHEMBL4212006 | 0.72 | PGR (0.61) | ARPGRCYP19A1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083267-A2 | STEROID-17,17-LACTOL DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |