Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LPL | P06858 | 4/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12313750 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1NFKB1MAPK1RAB9A | |
| SCHEMBL12313746 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1NFKB1MAPK1RAB9A | |
| SCHEMBL992778 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1NFKB1MAPK1RAB9A | |
| SCHEMBL10358431 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1NFKB1MAPK1RAB9A | |
| SCHEMBL1046903 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1NFKB1MAPK1RAB9A | |
| SCHEMBL753213 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1NFKB1MAPK1RAB9A | |
| SCHEMBL13475016 | 0.94 | NPC1 (0.55) | SMN1; SMN2NPC1NFKB1MAPK1RAB9A | |
| SCHEMBL12439871 | 0.94 | NPC1 (0.55) | SMN1; SMN2NPC1NFKB1MAPK1RAB9A | |
| SCHEMBL4911541 | 0.94 | NPC1 (0.55) | SMN1; SMN2NPC1NFKB1MAPK1RAB9A | |
| SCHEMBL15316152 | 0.93 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1NFKB1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7666956-B2 | Polymer | MERCK PATENT GMBH (DE) | 2010-02-23 | — | — | US | disclosed |
| US-7666956-B2 | Polymer | MERCK PATENT GMBH (DE) | 2010-02-23 | — | — | US | disclosed |