SCHEMBL15316152

SCHEMBL15316152

CCCCc1ccc(N(c2ccc(CCCC)cc2)c2ccc(N(c3ccc(C)cc3)c3ccc(Br)cc3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.46
NPC1 O15118 1/20 0.46
NFKB1 P19838 1/20 0.46
MAPK1 P28482 1/20 0.46
RAB9A P51151 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ALDH1A1 P00352 2/20 0.45
CA2 P00918 2/20 0.44
CA1 P00915 1/20 0.44
CNR2 P34972 1/20 0.43
TAAR1 Q96RJ0 2/20 0.43
SKP2 Q13309 1/20 0.42
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C19 P33261 1/20 0.40
KCNH2 Q12809 1/20 0.40
LPL P06858 3/20 0.40
LIPG Q9Y5X9 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14594274 1.00 SMN1; SMN2 (0.46) SMN1; SMN2NPC1NFKB1MAPK1RAB9A
SCHEMBL12669128 0.95 NPC1 (0.50) SMN1; SMN2NPC1NFKB1MAPK1RAB9A
SCHEMBL15025953 0.93 ALDH1A1 (0.48) SMN1; SMN2NPC1NFKB1MAPK1RAB9A
SCHEMBL992778 0.93 SMN1; SMN2 (0.51) SMN1; SMN2NPC1NFKB1MAPK1RAB9A
SCHEMBL10358431 0.93 SMN1; SMN2 (0.51) SMN1; SMN2NPC1NFKB1MAPK1RAB9A
SCHEMBL12313746 0.93 SMN1; SMN2 (0.51) SMN1; SMN2NPC1NFKB1MAPK1RAB9A
SCHEMBL12313750 0.93 SMN1; SMN2 (0.51) SMN1; SMN2NPC1NFKB1MAPK1RAB9A
SCHEMBL753213 0.93 SMN1; SMN2 (0.51) SMN1; SMN2NPC1NFKB1MAPK1RAB9A
SCHEMBL1046903 0.93 SMN1; SMN2 (0.51) SMN1; SMN2NPC1NFKB1MAPK1RAB9A
SCHEMBL13475015 0.93 SMN1; SMN2 (0.51) SMN1; SMN2NPC1NFKB1MAPK1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9269905-B2 Polymer compound having carbon cluster structure and organic device using same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-02-23 US disclosed
US-20130270545-A1 POLYMER COMPOUND HAVING CARBON CLUSTER STRUCTURE AND ORGANIC DEVICE USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-10-17 US disclosed