SCHEMBL753213

SCHEMBL753213

CCCCc1ccc(N(c2ccc(Br)cc2)c2ccc(N(c3ccc(Br)cc3)c3ccc(CCCC)cc3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.51
NPC1 O15118 1/20 0.51
NFKB1 P19838 1/20 0.51
MAPK1 P28482 1/20 0.51
RAB9A P51151 1/20 0.51
NFKB2 Q00653 1/20 0.51
RELA Q04206 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
CA2 P00918 2/20 0.50
CA1 P00915 1/20 0.50
TAAR1 Q96RJ0 3/20 0.48
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C19 P33261 1/20 0.44
LPL P06858 4/20 0.44
LIPG Q9Y5X9 4/20 0.44
ALDH1A1 P00352 2/20 0.44
HSD17B10 Q99714 2/20 0.44
HPGD P15428 1/20 0.44
HTR2A P28223 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12313750 1.00 SMN1; SMN2 (0.51) SMN1; SMN2NPC1NFKB1MAPK1RAB9A
SCHEMBL12313746 1.00 SMN1; SMN2 (0.51) SMN1; SMN2NPC1NFKB1MAPK1RAB9A
SCHEMBL13475015 1.00 SMN1; SMN2 (0.51) SMN1; SMN2NPC1NFKB1MAPK1RAB9A
SCHEMBL992778 1.00 SMN1; SMN2 (0.51) SMN1; SMN2NPC1NFKB1MAPK1RAB9A
SCHEMBL10358431 1.00 SMN1; SMN2 (0.51) SMN1; SMN2NPC1NFKB1MAPK1RAB9A
SCHEMBL1046903 1.00 SMN1; SMN2 (0.51) SMN1; SMN2NPC1NFKB1MAPK1RAB9A
SCHEMBL13475016 0.94 NPC1 (0.55) SMN1; SMN2NPC1NFKB1MAPK1RAB9A
SCHEMBL12439871 0.94 NPC1 (0.55) SMN1; SMN2NPC1NFKB1MAPK1RAB9A
SCHEMBL4911541 0.94 NPC1 (0.55) SMN1; SMN2NPC1NFKB1MAPK1RAB9A
SCHEMBL15316152 0.93 SMN1; SMN2 (0.46) SMN1; SMN2NPC1NFKB1MAPK1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110003271-B Process for producing aromatic compound 住友化学株式会社 2022-05-03 CN disclosed
US-9728724-B2 Polymer containing aldehyde groups, reaction and crosslinking of this polymer, crosslinked polymer, and electroluminescent device comprising this polymer MERCK PATENT GMBH (DE) 2017-08-08 US disclosed
US-9728724-B2 Polymer containing aldehyde groups, reaction and crosslinking of this polymer, crosslinked polymer, and electroluminescent device comprising this polymer MERCK PATENT GMBH (DE) 2017-08-08 US disclosed
US-9695274-B2 Polymers containing 2,7-pyrene structural units MERCK PATENT GMBH (DE) 2017-07-04 US disclosed
US-9695274-B2 Polymers containing 2,7-pyrene structural units MERCK PATENT GMBH (DE) 2017-07-04 US disclosed
EP-2871198-B1 METHOD FOR PRODUCING AROMATIC COMPOUND SUMITOMO CHEMICAL CO (JP) 2017-06-14 EP disclosed
EP-2401316-B1 POLYMER HAVING ALDEHYDE GROUPS, CONVERTING AND CROSS-LINKING OF SAID POLYMER, CROSS-LINKED POLYMER, AND ELECTROLUMINESCENT DEVICE COMPRISING SAID POLYMER MERCK PATENT GMBH (DE) 2017-05-24 EP disclosed
US-9644070-B2 Cross-linkable and cross-linked polymers, process for the preparation thereof, and the use thereof MERCK PATENT GMBH (DE) 2017-05-09 US disclosed
US-9644070-B2 Cross-linkable and cross-linked polymers, process for the preparation thereof, and the use thereof MERCK PATENT GMBH (DE) 2017-05-09 US disclosed
US-9574049-B2 Polymers, their preparation and uses CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-02-21 US disclosed
WO-2004034749-A1 OPTICAL DEVICE CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2004-04-22 WO disclosed
US-20040062930-A1 Electroactive polymers 3M INNOVATIVE PROPERTIES COMPANY 2004-04-01 US disclosed
WO-2004021463-A2 BUFFER LAYERS FOR ORGANIC ELECTROLUMINESCENT DEVICES AND METHODS OF MANUFACTURE AND USE 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-03-11 WO disclosed
US-20040004433-A1 Buffer layers for organic electroluminescent devices and methods of manufacture and use 3M INNOVATIVE PROPERTIES COMPANY 2004-01-08 US disclosed
US-20040002576-A1 Polymer compound and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED 2004-01-01 US disclosed
WO-2003095586-A1 POLYMERS THEIR PREPARATION AND USES CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2003-11-20 WO disclosed
EP-1344788-A1 Conjugated polymer comprising dibenzothiophene- or dibenzofuran-units and their use in polymer LEDs SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-09-17 EP disclosed
US-20030168656-A1 New polymer and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED 2003-09-11 US disclosed
US-20030154647-A1 Photoluminescent markers and methods for detection of such markers AMERICAN DYE SOURCE, INC. (CA) 2003-08-21 US disclosed
EP-1318163-A1 New polymer and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-06-11 EP disclosed