Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1394498 | 0.90 | THRB (0.67) | THRBMAPTL3MBTL1MAPK1NPC1 | |
| SCHEMBL29353897 | 0.90 | THRB (0.67) | THRBMAPTL3MBTL1MAPK1NPC1 | |
| SCHEMBL57955 | 0.90 | THRB (0.67) | THRBMAPTL3MBTL1MAPK1NPC1 | |
| SCHEMBL4223162 | 0.90 | THRB (0.67) | THRBMAPTL3MBTL1MAPK1NPC1 | |
| SCHEMBL13474931 | 0.86 | THRB (0.54) | THRBMAPTL3MBTL1MAPK1NPC1 | |
| SCHEMBL8746588 | 0.84 | THRB (0.82) | THRBMAPTL3MBTL1MAPK1NPC1 | |
| SCHEMBL8746592 | 0.84 | THRB (0.82) | THRBMAPTL3MBTL1MAPK1NPC1 | |
| SCHEMBL4159058 | 0.83 | THRB (1.00) | THRBMAPTL3MBTL1MAPK1NPC1 | |
| SCHEMBL29356344 | 0.83 | THRB (1.00) | THRBMAPTL3MBTL1MAPK1NPC1 | |
| SCHEMBL338695 | 0.83 | THRB (1.00) | THRBMAPTL3MBTL1MAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100047426-A1 | METHOD FOR MODULATING THE TASTE OF MATERIAL COMPOSITIONS CONTAINING AT LEAST ONE HIGH INTENSITY SWEETENER (HIS) | BASF SE (DE) | 2010-02-25 | — | — | US | disclosed |