Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6121987 | 0.89 | ALDH1A1 (0.41) | HRH3ALDH1A1TSHRGAALMNA | |
| SCHEMBL2528801 | 0.86 | ALDH1A1 (0.55) | HRH3ALDH1A1TSHRGAALMNA | |
| SCHEMBL20837049 | 0.84 | HRH3 (0.40) | HRH3ALDH1A1TSHRGAALMNA | |
| SCHEMBL27410305 | 0.84 | HRH3 (0.40) | HRH3ALDH1A1TSHRGAALMNA | |
| SCHEMBL30934937 | 0.84 | HRH3 (0.40) | HRH3ALDH1A1TSHRGAALMNA | |
| SCHEMBL18314385 | 0.84 | ALDH1A1 (0.46) | HRH3ALDH1A1TSHRGAALMNA | |
| SCHEMBL19023363 | 0.81 | CYP2C19 (0.47) | HRH3ALDH1A1TSHRGAALMNA | |
| SCHEMBL6121307 | 0.80 | LMNA (0.41) | HRH3ALDH1A1TSHRGAALMNA | |
| SCHEMBL345830 | 0.80 | SLC6A4 (0.43) | HRH3ALDH1A1TSHRGAALMNA | |
| SCHEMBL2394367 | 0.78 | ALDH1A1 (0.51) | HRH3ALDH1A1TSHRGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410247-B2 | Water-soluble phosphinothiol reagents | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-04-02 | — | — | US | disclosed |
| US-8410247-B2 | Water-soluble phosphinothiol reagents | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-04-02 | — | — | US | disclosed |
| US-20100048866-A1 | WATER-SOLUBLE PHOSPHINOTHIOL REAGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-02-25 | — | — | US | disclosed |
| US-20100048866-A1 | WATER-SOLUBLE PHOSPHINOTHIOL REAGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048866-A1 | WATER-SOLUBLE PHOSPHINOTHIOL REAGENTS | PTMS, PHOSPHO1, ACP1 | HRH3 3184/4885ALDH1A1 3577/4885TSHR 671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.