Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 6/20 | 0.31 |
| ▸ | PARP1 | P09874 | 6/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 6/20 | 0.31 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17568792 | 0.88 | KMT2A (0.38) | KMT2AALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL10305542 | 0.85 | KMT2A (0.37) | KMT2AALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL7533087 | 0.78 | KMT2A (0.40) | KMT2AALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL7524362 | 0.77 | POLB (0.38) | KMT2AALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL10305569 | 0.76 | KMT2A (0.36) | KMT2AALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL7536559 | 0.76 | KMT2A (0.42) | KMT2AALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL7536976 | 0.76 | KMT2A (0.38) | KMT2AALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL7527644 | 0.72 | POLB (0.46) | KMT2AALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL7532423 | 0.72 | ADAMTS5 (0.43) | KMT2AALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL7528739 | 0.70 | ATM (0.37) | KMT2AALDH1A1LMNASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2153832-A2 | Heterocyclic aspartyl protease inhibitors | SCHERING CORPORATION (US) | 2010-02-17 | — | — | EP | disclosed |