Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LYPLA1 | O75608 | 1/20 | 0.61 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12266287 | 0.86 | LYPLA1 (0.70) | LYPLA1LYPLA2KDM4ECYP1A2TSHR | |
| SCHEMBL12270590 | 0.83 | LYPLA1 (0.47) | LYPLA1LYPLA2KDM4ECYP1A2TSHR | |
| SCHEMBL12266416 | 0.82 | LYPLA1 (0.62) | LYPLA1LYPLA2KDM4ECYP1A2TSHR | |
| SCHEMBL13476009 | 0.82 | LYPLA1 (0.58) | LYPLA1LYPLA2KDM4ECYP1A2TSHR | |
| SCHEMBL12266311 | 0.81 | LYPLA1 (0.77) | LYPLA1LYPLA2KDM4ECYP1A2TSHR | |
| SCHEMBL13383655 | 0.81 | LYPLA1 (0.60) | LYPLA1LYPLA2KDM4ECYP1A2TSHR | |
| SCHEMBL12266378 | 0.79 | LYPLA1 (0.59) | LYPLA1LYPLA2KDM4ECYP1A2TSHR | |
| SCHEMBL17698458 | 0.78 | LYPLA1 (0.64) | LYPLA1LYPLA2KDM4ECYP1A2TSHR | |
| SCHEMBL12270908 | 0.78 | LYPLA1 (0.78) | LYPLA1LYPLA2KDM4ECYP1A2TSHR | |
| SCHEMBL12270830 | 0.77 | LYPLA1 (0.76) | LYPLA1LYPLA2KDM4ECYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018837-A2 | PROTEIN CROSS-LINKING INHIBITOR | 独立行政法人科学技術振興機構 (JP) | 2010-02-18 | — | — | WO | disclosed |
| WO-2010018836-A2 | POLYGLUTAMINE AGGREGATION INHIBITOR | 独立行政法人科学技術振興機構 (JP) | 2010-02-18 | — | — | WO | disclosed |