Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LYPLA1 | O75608 | 1/20 | 0.64 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12266287 | 0.82 | LYPLA1 (0.70) | LYPLA1LYPLA2CYP1A2TSHRKDM4E | |
| SCHEMBL12270908 | 0.81 | LYPLA1 (0.78) | LYPLA1LYPLA2CYP1A2TSHRKDM4E | |
| SCHEMBL12270830 | 0.79 | LYPLA1 (0.76) | LYPLA1LYPLA2CYP1A2TSHRKDM4E | |
| SCHEMBL13476010 | 0.78 | LYPLA1 (0.61) | LYPLA1LYPLA2CYP1A2TSHRKDM4E | |
| SCHEMBL12266301 | 0.78 | LYPLA1 (1.00) | LYPLA1LYPLA2CYP1A2TSHRKDM4E | |
| SCHEMBL17698460 | 0.77 | KDM4E (0.47) | LYPLA1LYPLA2CYP1A2TSHRKDM4E | |
| SCHEMBL13476042 | 0.77 | LYPLA1 (0.63) | LYPLA1LYPLA2CYP1A2TSHRKDM4E | |
| SCHEMBL13476023 | 0.77 | LYPLA1 (0.63) | LYPLA1LYPLA2CYP1A2TSHRKDM4E | |
| SCHEMBL12266416 | 0.76 | LYPLA1 (0.62) | LYPLA1LYPLA2CYP1A2TSHRKDM4E | |
| SCHEMBL14135146 | 0.76 | LYPLA1 (0.62) | LYPLA1LYPLA2CYP1A2TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961756-B1 | NOVEL BISBORON COMPOUND | JAPAN SCIENCE & TECH AGENCY (JP) | 2016-04-27 | — | — | EP | claimed |
| EP-1961756-B1 | NOVEL BISBORON COMPOUND | JAPAN SCIENCE & TECH AGENCY (JP) | 2016-04-27 | — | — | EP | disclosed |