SCHEMBL13477366

SCHEMBL13477366

CO/N=C(\C)C(=O)OCF

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13477370 0.83 MAPT (0.38) MAPT
SCHEMBL13319200 0.80 MAPT (0.53) MAPT
SCHEMBL23635709 0.80 MAPT (0.53) MAPT
SCHEMBL10020203 0.74
SCHEMBL13477368 0.70 ALDH1A1 (0.36) MAPT
SCHEMBL24073187 0.69 ALDH1A1 (0.37)
SCHEMBL14899148 0.68
SCHEMBL7532190 0.68
SCHEMBL7532185 0.68
SCHEMBL8439968 0.67 ALDH1A1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2149564-A1 SUBSTITUTED PYRIMIDINE ETHER COMPOUNDS AND THEIR USE Sinochem Corporation (CN) 2010-02-03 EP disclosed