Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13477370 | 0.83 | MAPT (0.38) | MAPT | |
| SCHEMBL8439968 | 0.79 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL8439966 | 0.79 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL13477371 | 0.77 | — | — | |
| SCHEMBL10020203 | 0.74 | — | — | |
| SCHEMBL8443559 | 0.71 | — | — | |
| SCHEMBL8443561 | 0.71 | — | — | |
| SCHEMBL13477366 | 0.70 | MAPT (0.38) | MAPT | |
| SCHEMBL22179885 | 0.67 | NPC1 (0.33) | TET2EGLN1 | |
| SCHEMBL10859600 | 0.67 | TRPA1 (0.35) | ALDH1A1MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170296508-A1 | Applications of Substituent Benzyloxy Group Containing Ether Compounds for Preparing Antitumor Drugs | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2017-10-19 | — | — | US | disclosed |
| EP-3040073-A1 | APPLICATIONS OF SUBSTITUENT BENZYLOXY GROUP CONTAINING ETHER COMPOUNDS FOR PREPARING ANTITUMOR DRUGS | Sinochem Corporation (CN) | 2016-07-06 | — | — | EP | disclosed |
| EP-2149564-A1 | SUBSTITUTED PYRIMIDINE ETHER COMPOUNDS AND THEIR USE | Sinochem Corporation (CN) | 2010-02-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170296508-A1 | Applications of Substituent Benzyloxy Group Containing Ether Compounds for Preparing Antitumor Drugs | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, MCL1, TPD52L2 | ALDH1A1 1819/4885MAPT 4870/4885MGAM 3610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.