Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 4/20 | 0.58 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PLAAT3 | P53816 | 3/20 | 0.41 |
| ▸ | PLAAT5 | Q96KN8 | 3/20 | 0.41 |
| ▸ | PLAAT2 | Q9NWW9 | 3/20 | 0.41 |
| ▸ | PLAAT4 | Q9UL19 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19085207 | 0.94 | BRS3 (0.52) | BRS3ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL13477455 | 0.88 | BRS3 (0.48) | BRS3MAPTNPC1RAB9ATAAR1 | |
| SCHEMBL20621075 | 0.85 | BRS3 (0.46) | BRS3ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL19085348 | 0.83 | MDM2 (0.43) | BRS3ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL20620984 | 0.83 | BRS3 (0.43) | BRS3ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL13477501 | 0.83 | NPC1 (0.48) | BRS3ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL20620544 | 0.83 | BRS3 (0.40) | BRS3ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL13477452 | 0.81 | BRS3 (0.44) | BRS3ALDH1A1HPGDKDM4EHTT | |
| SCHEMBL19085177 | 0.81 | BRS3 (0.46) | BRS3ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL20620985 | 0.81 | GALK1 (0.40) | BRS3ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2149561-A1 | TETRAHYDROISOQUINOLIN-1-ONE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2010-02-03 | — | — | EP | disclosed |