Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALK1 | P51570 | 1/20 | 0.40 |
| ▸ | BRS3 | P32247 | 4/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13477455 | 0.91 | BRS3 (0.48) | BRS3MAPTMRGPRX4THRBNPC1 | |
| SCHEMBL19085348 | 0.84 | MDM2 (0.43) | BRS3P2RX7MAPTALDH1A1TP53 | |
| SCHEMBL20621075 | 0.83 | BRS3 (0.46) | BRS3P2RX7MEN1KMT2AALDH1A1 | |
| SCHEMBL19085177 | 0.83 | BRS3 (0.46) | BRS3P2RX7MAPTALDH1A1NPC1 | |
| SCHEMBL13477442 | 0.81 | BRS3 (0.58) | BRS3MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL13477520 | 0.80 | RORC (0.43) | BRS3P2RX7ALDH1A1NPC1RAB9A | |
| SCHEMBL13477452 | 0.80 | BRS3 (0.44) | BRS3P2RX7KMT2AALDH1A1NPC1 | |
| SCHEMBL20620544 | 0.80 | BRS3 (0.40) | BRS3P2RX7MAPTALDH1A1THRB | |
| SCHEMBL20620611 | 0.79 | BRS3 (0.39) | BRS3P2RX7MAPTMEN1KMT2A | |
| SCHEMBL19085207 | 0.79 | BRS3 (0.52) | BRS3MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190000832-A1 | TETRAHYDROISOQUINOLIN-1-ONE DERIVATIVE OR SALT THEREOF | Selder Pharma Inc. (US) | 2019-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190000832-A1 | TETRAHYDROISOQUINOLIN-1-ONE DERIVATIVE OR SALT THEREOF | BRS3, BDKRB2, NTSR2 | GALK1 3899/4885BRS3 1/4885P2RX7 815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.