Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 15/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2897166 | 0.87 | GCK (0.57) | GCKKMT2AKCNH2 | |
| SCHEMBL1865137 | 0.86 | GCK (0.58) | GCKKMT2AEPHX1KCNH2 | |
| SCHEMBL1865136 | 0.86 | GCK (0.58) | GCKKMT2AEPHX1KCNH2 | |
| SCHEMBL1107388 | 0.86 | GCK (0.58) | GCKKMT2AEPHX1KCNH2 | |
| SCHEMBL2650823 | 0.85 | GCK (0.57) | GCKKMT2AEPHX1KCNH2 | |
| SCHEMBL2667236 | 0.85 | GCK (0.57) | GCKKMT2AEPHX1KCNH2 | |
| SCHEMBL2646180 | 0.85 | GCK (0.57) | GCKKMT2AEPHX1KCNH2 | |
| SCHEMBL2646260 | 0.85 | GCK (0.57) | GCKKMT2AEPHX1KCNH2 | |
| SCHEMBL1107300 | 0.84 | GCK (0.56) | GCKKMT2AEPHX1KCNH2 | |
| SCHEMBL2648154 | 0.83 | GCK (0.53) | GCKKMT2AEPHX1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2149550-A1 | NITROGEN-CONTAINING FIVE-MEMBERED HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2010-02-03 | — | — | EP | disclosed |