Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.54 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.48 |
| ▸ | NPY1R | P25929 | 2/20 | 0.48 |
| ▸ | NPY4R | P50391 | 2/20 | 0.48 |
| ▸ | NMUR2 | Q9GZQ4 | 4/20 | 0.48 |
| ▸ | NMUR1 | Q9HB89 | 4/20 | 0.48 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.46 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13144883 | 0.93 | OPRM1 (0.51) | OPRM1OPRK1NMUR2NMUR1NPFFR1 | |
| SCHEMBL13144534 | 0.92 | OPRM1 (0.61) | OPRM1OPRK1EPHA2 | |
| SCHEMBL13144377 | 0.88 | OPRM1 (0.48) | OPRM1OPRK1NMUR2NMUR1 | |
| SCHEMBL13478161 | 0.87 | OPRM1 (0.48) | OPRM1OPRK1NMUR2NMUR1 | |
| SCHEMBL13145229 | 0.85 | OPRM1 (0.47) | OPRM1OPRK1NMUR2NMUR1 | |
| SCHEMBL13144545 | 0.85 | MC4R (0.55) | — | |
| SCHEMBL13478177 | 0.85 | MC4R (0.55) | — | |
| SCHEMBL13144631 | 0.85 | MC4R (0.53) | — | |
| SCHEMBL13144549 | 0.82 | KISS1R (0.54) | OPRM1OPRK1 | |
| SCHEMBL13144540 | 0.82 | MC4R (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7659246-B2 | Treatment of osteoarthritis | PROMICS PTY LIMITED (AU) | 2010-02-09 | — | — | US | disclosed |