Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EBP | Q15125 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10082233 | 0.77 | THRB (0.35) | THRBMEN1KMT2A | |
| SCHEMBL18589032 | 0.77 | THRB (0.35) | THRBMEN1KMT2A | |
| SCHEMBL10251339 | 0.77 | THRB (0.35) | THRBMEN1KMT2A | |
| SCHEMBL1691466 | 0.77 | THRB (0.35) | THRBMEN1KMT2A | |
| SCHEMBL1742119 | 0.77 | THRB (0.35) | THRBMEN1KMT2A | |
| SCHEMBL24351770 | 0.77 | THRB (0.35) | THRBMEN1KMT2AEBP | |
| SCHEMBL20404228 | 0.77 | THRB (0.35) | THRBMEN1KMT2AEBP | |
| Hydrochloric Acid SCHEMBL20471310 | 0.76 | THRB (0.33) | THRBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL22264004 | 0.76 | THRB (0.33) | THRBMEN1KMT2A | |
| SCHEMBL18925536 | 0.76 | THRB (0.33) | THRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017046-A1 | PYRAZOLO[1,5-A]PYRIDINES AS MARK INHIBITORS | MERCK & CO., INC. (US) | 2010-02-11 | — | — | WO | disclosed |