Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15692423 | 0.79 | THRB (0.35) | THRBMEN1KMT2A | |
| SCHEMBL15984723 | 0.79 | THRB (0.35) | THRBMEN1KMT2A | |
| SCHEMBL14851202 | 0.79 | THRB (0.35) | THRBMEN1KMT2A | |
| SCHEMBL29243375 | 0.76 | THRB (0.36) | THRBMEN1KMT2A | |
| SCHEMBL13478486 | 0.76 | THRB (0.32) | THRBMEN1KMT2A | |
| SCHEMBL935597 | 0.74 | THRB (0.35) | THRBMEN1KMT2A | |
| SCHEMBL12493514 | 0.73 | — | — | |
| SCHEMBL12493513 | 0.73 | — | — | |
| SCHEMBL12493516 | 0.73 | — | — | |
| SCHEMBL17689134 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3176154-A1 | BENZAMIDES AND NICOTINAMIDES AS SYK MODULATORS | Portola Pharmaceuticals, Inc. (US) | 2017-06-07 | — | — | EP | disclosed |