Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1876090 | 0.90 | PLA2G2A (0.49) | MTNR1AMTNR1BHTR6PTGDR2HDAC6 | |
| SCHEMBL14623578 | 0.90 | PTGDR2 (0.45) | MTNR1AMTNR1BHTR6PTGDR2HDAC6 | |
| SCHEMBL13478778 | 0.90 | PTGDR2 (0.45) | MTNR1AMTNR1BHTR6PTGDR2HDAC6 | |
| SCHEMBL1875342 | 0.89 | PLA2G2A (0.51) | MTNR1AMTNR1BHTR6PTGDR2HDAC6 | |
| SCHEMBL1880121 | 0.88 | PTGDR2 (0.44) | MTNR1AMTNR1BHTR6PTGDR2HDAC6 | |
| SCHEMBL1875284 | 0.86 | PTGDR2 (0.42) | MTNR1AMTNR1BHTR6PTGDR2 | |
| SCHEMBL1875281 | 0.86 | PTGDR2 (0.42) | MTNR1AMTNR1BHTR6PTGDR2 | |
| SCHEMBL1879708 | 0.86 | PTGDR2 (0.42) | MTNR1AMTNR1BHTR6PTGDR2 | |
| SCHEMBL1879305 | 0.85 | PLA2G2A (0.49) | MTNR1AMTNR1BHTR6PTGDR2HDAC6 | |
| SCHEMBL13478781 | 0.85 | MTNR1A (0.51) | MTNR1AMTNR1BHTR6PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902026-B1 | TETRAHYDROCARBAZOLE DERIVATIVES USEFUL AS ANDROGEN RECEPTOR MODULATORS (SARM) | LILLY CO ELI (US) | 2010-02-17 | — | — | EP | disclosed |